Evidence map›Paper›PMID 12842077›Full record

ArticleCancer cell2003

Matrix reloaded to circulation hits the tumor target.

Sara A Wickström, Jorma Keski-Oja, Kari Alitalo

Open access · bronzeAbstract readCommentEditorial
PubMed Publisher
In one paragraph

Article in Cancer cell, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Regulation of p38 MAP kinase by anastellin is independent of anastellin's effect on matrix fibronectin.Matrix biology : journal of the International Society for Matrix Biology · 2009
    Article
  3. Molecular changes in the vasculature of injured tissues.The American journal of pathology · 2007
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sara A Wickström
Jorma Keski-Oja
Kari Alitalo
University of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proteolytic fragments of various components of the extracellular matrix exhibit antiangiogenic activity via interaction with endothelial cell surface integrins. Kalluri and coworkers (this issue of Cancer Cell) use gene-targeted mice to show a physiological role for a carboxy-terminal fragment of collagen IV in the regulation of tumor angiogenesis.

Indexed as

AnimalsCollagen Type IVExtracellular MatrixHumansMatrix Metalloproteinase 9MiceMice, KnockoutNeoplasmsNeovascularization, PathologicCollagen Type IVMatrix Metalloproteinase 9

Identifiers

PMID12842077
OpenAlexW2002472034

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.