ArticleMolecular and cellular biochemistry2003
Correlation between the extent of coronary atherosclerosis and lipid profile.
Article in Molecular and cellular biochemistry, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 48 citations in OpenAlex.
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- Two-Sample Mendelian Randomization Study of Lipid levels and Ischemic Heart Disease.Korean circulation journal · 2020Article
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- Association of plasma fatty acid alteration with the severity of coronary artery disease lesions in Tunisian patients.Lipids in health and disease · 2017Article
- Effects and mechanism of Xin Mai Jia in a rabbit model of atherosclerosis.Experimental and therapeutic medicine · 2015Article
- Comparison of microalbuminuria with hs-CRP and low density lipoprotein levels in nondiabetic, nonhypertensive myocardial infarction patients.Journal of cardiovascular disease research · 2012Article
- High serum advanced glycation end-products predict coronary artery disease irrespective of arterial stiffness in diabetic patients.Korean circulation journal · 2012Article
- Paraoxonase Arg 192 allele is an independent risk factor for three-vessel stenosis of coronary artery disease.Molecular biology reports · 2011Article
- Vasculoprotective effects of rosiglitazone through modulating renin-angiotensin system in vivo and vitro.Cardiovascular diabetology · 2011Article
- Correlation between myocardial enzyme serum levels and markers of inflammation with severity of coronary artery disease and Gensini score: a hospital-based, prospective study in Greek patients.Clinical interventions in aging · 2008Article
- Association of lipid profile test values, type-2 diabetes mellitus, and periodontitis.Indian journal of dentistryArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increased concentration of low density lipoprotein (LDL) cholesterol or decreased level of high density lipoprotein (HDL) cholesterol are important risk factors for coronary atherosclerosis. However, an independent association of triglycerides (TG) with atherosclerosis is uncertain. The aim of this prospective study was to evaluate the relationship between serum lipid levels and the extent of coronary atherosclerosis in patients with suspected coronary artery disease (CAD) and no previous myocardial infarction who were not treated with lipids lowering therapy or low-lipid diet. The study was conducted in 141 patients (53.6 +/- 7.8 years old; 32 female) who underwent a routine coronary angiography for CAD diagnosis. A modified angiographic Gensini Score (GS) was used to reflect the extent of coronary atherosclerosis. Fasting serum lipid concentrations were determined using cholesterol esterase/peroxidase (CHOD/PAP) enzymatic method for total cholesterol and its fractions and lipase glycerol kinase (GPO/PAP) enzymatic method TG evaluation. The association of Gensini Score with variables characterising lipid profile was analysed with the use of Pearson correlation (r co-efficient; p value). GS was positively correlated with total cholesterol (r = 0.404; p < 0.001), LDL cholesterol (r = 0.484; p < 0.001 ) and TG (r = 0.235; p = 0.005). There was a negative correlation between Gensini Score and HDL cholesterol (r = -0.396; p < 0.001). In angina pectoris patients with no previous myocardial infarction, the extent of coronary atherosclerosis is positively correlated with pro-atherogenic lipids, i.e. total cholesterol, LDL cholesterol and TG and negatively correlated with antiatherogenic HDL cholesterol.
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12841339W1493275217What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.