ArticleArchives of dermatological research1992
Soluble CD14 but not interleukin-6 is a new marker for clinical activity in atopic dermatitis.
Article in Archives of dermatological research, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 75 citations in OpenAlex.
- FcεRII (CD23) in dermatological disorders: structure, function, and clinical implications.Frontiers in allergy · 2026Review
- Elevated acute phase proteins reflect peripheral inflammation and disease severity in patients with amyotrophic lateral sclerosis.Scientific reports · 2020Article
- Soluble macrophage biomarkers indicate inflammatory phenotypes in patients with knee osteoarthritis.Arthritis & rheumatology (Hoboken, N.J.) · 2015Article
- Clinical proteomics identifies urinary CD14 as a potential biomarker for diagnosis of stable coronary artery disease.PloS one · 2015Article
- Diagnostic value of soluble CD14 subtype (sCD14-ST) presepsin for the postmortem diagnosis of sepsis-related fatalities.International journal of legal medicine · 2013Article
- Single nucleotide polymorphisms in the promoter of the gene encoding the lipopolysaccharide receptor CD14 are associated with bacterial diarrhea in US and Canadian travelers to Mexico.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2011Article
- Circulating levels of the innate and humoral immune regulators CD14 and CD23 are associated with adult glioma.Cancer research · 2010Article
- Soluble CD14: role in atopic disease and recurrent infections, including otitis media.Current allergy and asthma reports · 2007Review
- Association of CD14 promoter polymorphisms and soluble CD14 levels in mite allergen sensitization of children in Taiwan.Journal of human genetics · 2006Article
- Increased levels of circulating soluble CD14 in Kawasaki disease.Clinical and experimental immunology · 2000Article
- Soluble CD14 activates monocytic cells independently of lipopolysaccharide.Infection and immunity · 1998Article
- Soluble CD14 mediates lipopolysaccharide-induced intercellular adhesion molecule 1 expression in cultured human gingival fibroblasts.Infection and immunity · 1996Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Levels of soluble IL-2 receptors, IL-6, soluble CD23, soluble CD14 and ECP (eosinophilic cationic protein) were measured as markers of T-cell, B-cell, monocyte and eosinophilic leucocyte activation in 26 patients with atopic dermatitis (AD) on admission to (A) and at discharge from (D) the Department of Dermatology in Zurich. The serum levels of sIL-2R, IL-6, sCD23, sCD14 and ECP were significantly elevated in AD patients in comparison with the normal values of healthy donors. A significant decrease in sIL-2R (p = 0.0093) and in sCD14 (p = 0.0134) levels was demonstrated between A and D, correlating with the improvement in the skin intensity score (SIS). In addition, a significant correlation of the sCD14 levels and the SIS at A was demonstrated (p = 0.0415). These results also incriminate monocytes in the pathogenesis of AD, indicating that, besides sIL-2R and ECP, SCD14 could also be a possible marker for the disease activity.
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Registered trials
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