Evidence map›Paper›PMID 12840852›Full record

ArticleJournal of Tongji Medical University = Tong ji yi ke da xue xue bao1999

Myosin-induced autoimmune myocarditis in BALB/C mice.

Z Wang, Y Liao, J Dong, S Li, J Wang, Y Tu

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1999. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Effect of anti-cardiac myosin antibody on prognosis of patients with acute myocardial infarction.Journal of Tongji Medical University = Tong ji yi ke da xue xue bao · 2000
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Z WangInstitute of Cardiovascular Diseases, Tongji Medical University, Wuhan 430022.
Y Liao
J Dong
S Li
J Wang
Y Tu
Tongji Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Experimental mice were immunized with cardiac myosin and complete Freund's adjuvant (CFA) on days 0, 7 and 30 and control mice were immunized with CFA. Sera and myocardium samples were harvested on days 15, 21 and 120 after the first immunization. Pathological findings demonstrated that there were necrosis and inflammatory infiltration in acute stage and fibrosis mainly in chronic stage of experimental group. Anti-myosin antibodies were also found in sera of experimental mice, but not in control group. Our study showed that cardiac myosin served as an autoantigen to provoke autoimmunity and lead to the transformation of VMC into DCM.

Indexed as

Disease Models, AnimalMyocarditisAnimalsAutoantibodiesFemaleMaleMiceMice, Inbred BALB CMyosinsAutoantibodiesMyosins

Identifiers

PMID12840852
OpenAlexW96738475

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.