Evidence map›Paper›PMID 12839823›Full record

ArticleApplied and environmental microbiology2003

Oligonucleotide probes that detect quantitatively significant groups of butyrate-producing bacteria in human feces.

Georgina L Hold, Andreas Schwiertz, Rustam I Aminov, Michael Blaut, Harry J Flint

Open access · greenAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 149 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
149citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

149 citing papers in PubMed, 1 synthesis or guideline pooled it, 336 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Review
  6. Article
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  15. Article
  16. Article
  17. Observational
  18. Article
  19. International journal of molecular sciences · 2025
    Article
  20. Review

89 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Georgina L HoldRowett Research Institute, Bucksburn, Aberdeen AB21 9SB, Scotland, UK. g.l.hold@abdn.ac.uk
Andreas Schwiertz
Rustam I Aminov
Michael Blaut
Harry J Flint
German Institute of Human Nutrition · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

16S rRNA-targeted oligonucleotide probes were designed for butyrate-producing bacteria from human feces. Three new cluster-specific probes detected bacteria related to Roseburia intestinalis, Faecalibacterium prausnitzii, and Eubacterium hallii at mean populations of 2.3, 3.8, and 0.6%, respectively, in samples from 10 individuals. Additional species-level probes accounted for no more than 1%, with a mean of 7.7%, of the total human fecal microbiota identified as butyrate producers in this study. Bacteria related to E. hallii and the genera Roseburia and Faecalibacterium are therefore among the most abundant known butyrate-producing bacteria in human feces.

Indexed as

Oligonucleotide ProbesAdultButyratesEubacteriumFecesFemaleFusobacteriumHumansMaleMiddle AgedPolymerase Chain ReactionSpecies SpecificityButyratesOligonucleotide Probes

Identifiers

PMID12839823
PMCPMC165216
OpenAlexW2153896859

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.