ArticleApplied and environmental microbiology2003
Presence of viral genomes in mineral water: a sufficient condition to assume infectious risk?
Article in Applied and environmental microbiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 103 citations in OpenAlex.
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- Fate of SARS-CoV-2 coronavirus in wastewater treatment sludge during storage and thermophilic anaerobic digestion.Environmental research · 2022Article
- Somatic coliphages are conservative indicators of SARS-CoV-2 inactivation during heat and alkaline pH treatments.The Science of the total environment · 2021Article
- Coliphages as Indicators for the Microbial Quality of Treated Wastewater Effluents.Food and environmental virology · 2021Article
- Free Chlorine and Peroxynitrite Alter the Capsid Structure of Human Norovirus GII.4 and Its Capacity to Bind Histo-Blood Group Antigens.Frontiers in microbiology · 2021Article
- F-Specific RNA Bacteriophages Model the Behavior of Human Noroviruses during Purification of Oysters: the Main Mechanism Is Probably Inactivation Rather than Release.Applied and environmental microbiology · 2020Article
- Article
- Quantification of human adenovirus and norovirus in river water in the north-east of France.Environmental science and pollution research international · 2018Article
- F-Specific RNA Bacteriophages, Especially Members of Subgroup II, Should Be Reconsidered as Good Indicators of Viral Pollution of Oysters.Applied and environmental microbiology · 2018Article
- The Effect of Heat and Free Chlorine Treatments on the Surface Properties of Murine Norovirus.Food and environmental virology · 2017Article
- In Situ Dynamics of F-Specific RNA Bacteriophages in a Small River: New Way to Assess Viral Propagation in Water Quality Studies.Food and environmental virology · 2017Article
- The Effect of Heat on the Physicochemical Properties of Bacteriophage MS2.Food and environmental virology · 2016Article
- Relevance of F-Specific RNA Bacteriophages in Assessing Human Norovirus Risk in Shellfish and Environmental Waters.Applied and environmental microbiology · 2016Article
- Occurrence of and Sequence Variation among F-Specific RNA Bacteriophage Subgroups in Feces and Wastewater of Urban and Animal Origins.Applied and environmental microbiology · 2015Article
- Absolute Humidity Influences the Seasonal Persistence and Infectivity of Human Norovirus.Applied and environmental microbiology · 2014Article
- Prevalence of human noroviruses in frozen marketed shellfish, red fruits and fresh vegetables.Food and environmental virology · 2014Article
- Comparison of fecal indicators with pathogenic bacteria and rotavirus in groundwater.The Science of the total environment · 2012Article
- Occurrence, survival, and persistence of human adenoviruses and F-specific RNA phages in raw groundwater.Applied and environmental microbiology · 2010Article
- Use of propidium monoazide in reverse transcriptase PCR to distinguish between infectious and noninfectious enteric viruses in water samples.Applied and environmental microbiology · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Appropriate interpretation of a positive reverse transcription-PCR is an important issue for virus-related health hazard assessment because viral genomes and infectious viruses exhibit different behavior patterns in water. In this context, using Poliovirus 1 and Feline calicivirus f9 as examples of enteric viruses, first we demonstrated that the stability of infectious viruses is greatly affected by the temperature of mineral water (10, 20, and 35 degrees C) and that, in contrast, temperature has little effect on the corresponding genomes. Second, we demonstrated that infectious particles are degraded more rapidly than viral genomes at all temperatures studied. At 35 degrees C, Poliovirus 1 infectivity was reduced 4 logs after only 19 days, while an equivalent reduction would have taken 75 years (according to the model applied) for the viral genome. Contradictory conclusions can also be drawn concerning the sensitivity of viral serotypes depending on whether the infectious virus or the viral genome is considered. The Feline calicivirus f9 genome is more resistant than the Poliovirus 1 genome, whereas the opposite is true for the corresponding infectious viruses. Thus, we concluded that a positive test for a viral genome in mineral water must be interpreted with utmost caution because of the lack of a correlation between the presence of viral genomes and viral infectivity. Detection of viral genomes may be necessary to identify infectious risk for the human population, but it cannot be considered sufficient.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.