Evidence map›Paper›PMID 12836698›Full record

ArticleJournal of structural and functional genomics2003

Phylogenetic analysis of the mammalian Hoxc8 non-coding region.

Chang-Bae Kim, Cooduvalli S Shashikant, Kenta Sumiyama, Wayne C H Wang, Chris T Amemiya, Frank H Ruddle

Abstract read
PubMed
In one paragraph

Article in Journal of structural and functional genomics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Chang-Bae KimDepartment of Molecular, Cellular, and Developmental Biology, Yale University, PO Box 208103, New Haven, CT 06520, USA.
Cooduvalli S Shashikant
Kenta Sumiyama
Wayne C H Wang
Chris T Amemiya
Frank H Ruddle
Yale University · USKorea Research Institute of Bioscience and Biotechnology · KRPennsylvania State University · US

Funding

Genomics Resources and Infrastucture for the ZebrafishR24RR014085 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI AMEMIYA, CHRIS T. · 2000 to 2011
$3.3M
GENETIC ANALYSIS OF SOMATIC CELL POPULATIONR01GM009966 · NIGMS · YALE UNIVERSITY · PI RUDDLE, FRANK H · 1985 to 2006
$2.2M
GENETIC ANALYSIS OF SOMATIC CELL POPULATIONR37GM009966 · NIGMS · YALE UNIVERSITY · PI RUDDLE, FRANK H · 1990 to 1994
–
NCRR NIH HHS R24-RR14085NIGMS NIH HHS GM09966
6 · The paper itself

Abstract

The non-coding intergenic regions of Hox genes are remarkably conserved among mammals. To determine the usefulness of this sequence for phylogenetic comparisons, we sequenced an 800-bp fragment of the Hoxc9-Hoxc8 intergenic region from several species belonging to different mammalian clades. Results obtained from the phylogenetic analysis are congruent with currently accepted mammalian phylogeny. Additionally, we found a TC mini satellite repeat polymorphism unique to felines. This polymorphism may serve as a useful marker to differentiate between mammalian species or as a genetic marker in feline matings. This study demonstrates usefulness of a comparative approach employing non-coding regions of Hox gene complexes.

Indexed as

DNA, IntergenicPhylogenyAnimalsEnhancer Elements, GeneticEvolution, MolecularGenetic VariationHomeodomain ProteinsHumansMammalsSequence AlignmentSequence Analysis, DNADNA, IntergenicHomeodomain ProteinsHoxc6 protein, mouseHOXC8 protein, human

Identifiers

PMID12836698
OpenAlexW1786496133

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.