ReviewJournal of structural and functional genomics2003
Dopamine receptors for every species: gene duplications and functional diversification in Craniates.
Review in Journal of structural and functional genomics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 46 citations in OpenAlex.
- The Promising Role of Synthetic Flavors in Advancing Fish Feeding Strategies: A Focus on Adult Female Zebrafish (Animals : an open access journal from MDPI · 2024Article
- The Application of Synthetic Flavors in Zebrafish (Animals : an open access journal from MDPI · 2023Article
- Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens.Cell reports · 2022Article
- The Genome of the Marine Rotifer Brachionus manjavacas: Genome-Wide Identification of 310 G Protein-Coupled Receptor (GPCR) Genes.Marine biotechnology (New York, N.Y.) · 2022Article
- Paternal exposure to a common pharmaceutical (Ritalin) has transgenerational effects on the behaviour of Trinidadian guppies.Scientific reports · 2021Article
- Evolution of dopamine receptors: phylogenetic evidence suggests a later origin of the DRDPeerJ · 2018Article
- Expression of a Novel D4 Dopamine Receptor in the Lamprey Brain. Evolutionary Considerations about Dopamine Receptors.Frontiers in neuroanatomy · 2015Article
- Identification of dopamine receptors across the extant avian family tree and analysis with other clades uncovers a polyploid expansion among vertebrates.Frontiers in neuroscience · 2015Article
- Forebrain dopamine neurons project down to a brainstem region controlling locomotion.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Evolution of dopamine receptor genes of the D1 class in vertebrates.Molecular biology and evolution · 2013Article
- Conserved role of dopamine in the modulation of behavior.Communicative & integrative biology · 2012Article
- The dopamine D2 receptor gene in lamprey, its expression in the striatum and cellular effects of D2 receptor activation.PloS one · 2012Article
- PharmGKB summary: dopamine receptor D2.Pharmacogenetics and genomics · 2011Article
- The evolution of dopamine systems in chordates.Frontiers in neuroanatomy · 2011Article
- A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-orphanization.BMC bioinformatics · 2010Article
- Dopaminergic system in birdsong learning and maintenance.Journal of chemical neuroanatomy · 2010Review
- Molecular cloning and characterization of crustacean type-one dopamine receptors: D1alphaPan and D1betaPan.Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology · 2006Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The neuromodulatory effects of dopamine on the central nervous system of craniates are mediated by two classes of G protein-coupled receptors (D1 and D2), each comprising several subtypes. A systematic isolation and characterization of the D1 and D2-like receptors was carried out in most of the Craniate groups. It revealed that two events of gene duplications took place during vertebrate evolution, before or simultaneously to the emergence of Gnathostomes. It led to the conservation of two-to-four paralogous receptors (subtypes), depending on the species. Additional duplication of dopamine receptor gene occurred independently in the teleost fish lineage. Duplicated genes were maintained in most of the vertebrate groups, certainly by the acquisition of a few functional characters, specific of each subtypes, as well as by discrete changes in their expression territories in the brain. The evolutionary scenario elaborated from these data suggests that receptor gene duplications were the necessary conditions for the expansion of vertebrate forebrain to occur, allowing dopamine systems to exert their fundamental role as modulator of the adaptive capabilities acquired by vertebrate species.
Indexed as
Identifiers
12836695W1578805066What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.