ArticleWiener medizinische Wochenschrift (1946)2003
Cost-effectiveness in diagnosis of patients with long-standing fever.
Article in Wiener medizinische Wochenschrift (1946), 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Pyrexia of unknown origin (PUO) and the cost of care in a tertiary care institute in Sri Lanka.BMC health services research · 2023Article
- Recommendations for the inclusion of Fabry disease as a rare febrile condition in existing algorithms for fever of unknown origin.Internal and emergency medicine · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionIt is difficult to make an adequate diagnosis regarding patients with fever of unknown origin (FUO). The cases require time-consuming and costly investigations. Our study features a cost-effectiveness analysis and the development of an alternative diagnostic model. The diagnostic programmes include: serological and microbiological tests, blood laboratory test, radiological, histopathological and radionuclide tests. PATIENTS AND
methodsFor 100 hospitalized patients with fever (group A: > 38.0 degrees C for as long as 7 days; group B: > 38.3 degrees C for 3 weeks), the various results of clinical investigations were obtained, and the costs of a three-step programme for the four main diagnoses, including the diagnostic value, were evaluated.
resultsThere was no significant difference between male and female patients, or patients < 35 vs. > 35, and < 50 vs. > 50 years. Infections were found in 46%, neoplasma and collagen-vascular disease/autoimmune disorders in 10% each, and other diseases in 20% of all patients. The third diagnostic programme was the most expensive in all four disease categories. In total, 30, 34, and 22 patients were diagnosed by the three diagnostic steps, respectively. In 14 patients no diagnosis was found. The overall cost of the three diagnostic programmes was 359, 1,996 and 3,496 EUR, respectively.
conclusionsIn the majority of the cases (64%), the first and second diagnostic programmes result in a diagnosis. The investigations of the third diagnostic programme are more accurate, more expensive, and result in a diagnosis, mainly in patients of group B. Our proposed new diagnostic model would save 134, 746, and 558 EUR for each diagnostic step, respectively.
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