ReviewEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2004
Etiopathogenesis of cholesteatoma.
Review in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
110 citing papers in PubMed, 1 synthesis or guideline pooled it, 302 citations in OpenAlex.
- Health-related quality of life after otologic surgical treatment for chronic otitis media: systematic review.Frontiers in neurology · 2023Pooled it
- Imaging findings in auto-atticotomy.AJNR. American journal of neuroradiology · 2014Trial
- Audiometric indicators of cochlear involvement in chronic suppurative otitis media with and without cholesteatoma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Mastoid cortex osteoma associated with middle-ear and mastoid cholesteatoma: a case report.Journal of medicine and life · 2026Article
- Surgical Techniques and Materials Used in the Treatment of Complicated Otomastoiditis: A Systematic Review.Journal of clinical medicine · 2026Review
- Mid- to long-term outcomes of the surgical treatment of 20 middle ear cholesteatomas in 18 French bulldogs.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2026Article
- Primary Intracranial Cholesteatoma Presenting as a Cerebellar Mass Without Otologic Symptoms.Cureus · 2026Article
- Cholesteatoma: An Updated Review of Molecular Pathogenesis and Potential Therapeutic Directions.Current medicinal chemistry · 2026Review
- Article
- Prevalence of Cholesteatoma in School Children of Nepal.International archives of otorhinolaryngology · 2025Article
- Balloon Eustachian Tuboplasty: A Systematic Review of Technique, Safety, and Clinical Outcomes in Chronic Obstructive Eustachian Tube Dysfunction.Healthcare (Basel, Switzerland) · 2025Review
- Investigation of Keratinized Squamous Epithelium from Mastoid Cortical Bone Dust in Patients with or without Cholesteatoma.Turkish archives of otorhinolaryngology · 2025Article
- The Ponto Bone-Anchored Hearing System - Benefits Following Radical Mastoidectomy.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Modern aspects of diagnosing purulent pathology of the ear (Review of cases of middle ear cholesteatoma using non-EPI DWI MRI).Journal of otology · 2025Review
- Epidemiology of Cholesteatoma in the UK Biobank.Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery · 2025Article
- Canal Wall Down Timpanoplasty with Partial Mastoid Obliteration in Children and Adults Affected by Chronic Otitis Media with Cholesteatoma.The journal of international advanced otology · 2025Article
- Comprehensive Management of Cholesteatoma in Otitis Media: Diagnostic Challenges, Imaging Advances, and Surgical Outcome.Journal of clinical medicine · 2024Article
- Evaluation of the Role of Myofibroblast and Fibronectin in the Aetiopathogenesis of Cholesteatoma.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Radiological Evaluation of Middle Cranial Fossa Dura in Patients with Unilateral Cholesteatoma.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Efficacy of Otoendoscopy for Residual Cholesteatoma Detection During Microscopic Chronic Ear Surgery.The journal of international advanced otology · 2024Article
50 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cholesteatoma is a destructive lesion of the temporal bone that gradually expands and causes complications by erosion of the adjacent bony structures. Bone resorption can result in destruction of the ossicular chain and otic capsule with consecutive hearing loss, vestibular dysfunction, facial paralysis and intracranial complications. Surgery is the only treatment of choice. The etiopathogenesis of cholesteatoma, however, is still controversial. This review was designed to understand the reasons for these disparities and to reduce or eliminate them. Future studies focused on developmental, epidemiological, hormonal and genetic factors as well as on treatment are likely to contribute to further understanding of cholesteatoma pathogenesis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.