ReviewEMBO reports2003
DNA replication: a complex matter.
Review in EMBO reports, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 60 citations in OpenAlex.
- Increased replication-associated single-stranded DNA promotes formaldehyde-induced mutagenesis.bioRxiv : the preprint server for biology · 2026Article
- Article
- The bacterial replisome has factory-like localization.Current genetics · 2018Review
- Partial Purification of a Megadalton DNA Replication Complex by Free Flow Electrophoresis.PloS one · 2016Article
- Relationship between DNA replication and the nuclear matrix.Genes to cells : devoted to molecular & cellular mechanisms · 2013Review
- Role of androgen receptor in progression of LNCaP prostate cancer cells from G1 to S phase.PloS one · 2013Article
- ATM protein kinase: the linchpin of cellular defenses to stress.Cellular and molecular life sciences : CMLS · 2011Review
- Processivity factor of DNA polymerase and its expanding role in normal and translesion DNA synthesis.Biochimica et biophysica acta · 2010Review
- Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels.The Journal of cell biology · 2010Article
- Spatial regulation and organization of DNA replication within the nucleus.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2010Review
- Characterization of RNA primers synthesized by the human breast cancer cell DNA synthesome.Journal of cellular biochemistry · 2009Article
- ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance.Cancer research · 2008Article
- A highly conserved family of inactivated archaeal B family DNA polymerases.Biology direct · 2008Article
- Enzymes used in molecular biology: a useful guide.Journal of cell communication and signaling · 2008Article
- Interactions and subcellular distribution of DNA replication initiation proteins in eukaryotic cells.Molecular genetics and genomics : MGG · 2007Article
- Human base excision repair complex is physically associated to DNA replication and cell cycle regulatory proteins.Nucleic acids research · 2007Article
- The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase.Nucleic acids research · 2007Article
- Live-cell imaging reveals replication of individual replicons in eukaryotic replication factories.Cell · 2006Article
- The human stress-activated protein kin17 belongs to the multiprotein DNA replication complex and associates in vivo with mammalian replication origins.Molecular and cellular biology · 2005Article
- Studying multiprotein complexes by multisignal sedimentation velocity analytical ultracentrifugation.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In eukaryotic cells, the essential function of DNA replication is carried out by a network of enzymes and proteins, which work together to rapidly and accurately duplicate the genetic information of the cell. Many of the components of this DNA replication apparatus associate with other cellular factors as components of multiprotein complexes, which act cooperatively in networks to regulate cell cycle progression and checkpoint control, but are distinct from the pre-replication complexes that associate with the origins and regulate their firing. In this review, we summarize current knowledge about the composition and dynamics of these large multiprotein complexes in mammalian cells and their relationships to the replication factories.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.