ReviewEnvironmental health perspectives2003
Environmental pollutants and breast cancer.
Review in Environmental health perspectives, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
77 citing papers in PubMed, 3 syntheses or guidelines pooled it, 301 citations in OpenAlex.
- Occupational Exposure to Benzene and Risk of Breast Cancer: Systematic Review and Meta-Analysis.La Medicina del lavoro · 2024Pooled it
- Urban Neighborhood and Residential Factors Associated with Breast Cancer in African American Women: a Systematic Review.Hormones & cancer · 2018Pooled it
- Environmental Polychlorinated Biphenyl Exposure and Breast Cancer Risk: A Meta-Analysis of Observational Studies.PloS one · 2015Pooled it
- The Complex Path from Mammary Ductal Hyperplasia to Breast Cancer: Elevated Malignancy Risk in Atypical Forms.Biomedicines · 2026Review
- Spatial Patterns of Breast Cancer Risk Associated with Industrial and Environmental Pollutants: A Scoping Review.Toxics · 2026Review
- Comment on: "The role of dermocosmetics in the management of cancer-related skin toxicities".Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- Review
- Review
- Evaluating the impact of Carbon Emission Trading Policy on pan-cancer incidence among middle-aged and elderly populations: a quasi-natural experiment.Environmental health and preventive medicine · 2025Article
- Heavy-metal associated breast cancer and colorectal cancer hot spots and their demographic and socioeconomic characteristics.Cancer causes & control : CCC · 2024Article
- Theranostics Using MCM-41-Based Mesoporous Silica Nanoparticles: Integrating Magnetic Resonance Imaging and Novel Chemotherapy for Breast Cancer Treatment.International journal of molecular sciences · 2024Article
- Urinary Concentrations of Endocrine-Disrupting Metals and Prevalent Breast Cancer in US Women.Biological trace element research · 2023Article
- Small fish consumption in rural Myanmar.Maritime studies : MAST · 2023Article
- Enhanced Tribocatalytic Degradation of Organic Pollutants by ZnO Nanoparticles of High Crystallinity.Nanomaterials (Basel, Switzerland) · 2022Article
- Urinary parabens and breast cancer risk: Modification by LINE-1 and LUMA global DNA methylation, and associations with breast cancer defined by tumor promoter methylation status.Molecular carcinogenesis · 2022Article
- Assessing the health hazard originated via pesticide chemicals in human through rabbit model in agricultural production system in Bangladesh.BMC pharmacology & toxicology · 2022Article
- An overview of organic contaminants in indoor dust, their health impact, geographical distribution and recent extraction/analysis methods.Environmental geochemistry and health · 2022Review
- Review
- Effects of Organochlorine Pesticide Residues in Maternal Body on Infants.Frontiers in endocrinology · 2022Review
- Monitoring estrogen and androgen residues from livestock farms in Phayao Lake, Thailand.Environmental monitoring and assessment · 2021Article
17 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Breast cancer is the most common cancer in women and the leading cause of cancer death among women 35-54 years of age. Rising incidence, increased risk among migrants to higher risk regions, and poor prediction of individual risk have prompted a search for additional modifiable factors. Risk factors for breast cancer include reproductive characteristics associated with estrogen and other hormones, pharmaceutical hormones, and activities such as alcohol use and lack of exercise that affect hormone levels. As a result, investigation of hormonally active compounds in commercial products and pollution is a priority. Compounds that cause mammary tumors in animals are additional priorities. Animal models provide insight into possible mechanisms for effects of environmental pollutants on breast cancer and identify chemical exposures to target in epidemiologic studies. Although few epidemiologic studies have been conducted for chemical exposures, occupational studies show associations between breast cancer and exposure to certain organic solvents and polycyclic aromatic hydrocarbons (PAHs). Population-based studies have been limited to a few organochlorine compounds and PAHs and have been mostly negative. A variety of challenges in studies of breast cancer and the environment may have contributed to negative findings. Lack of exposure assessment tools and few hypothesis-generating toxicologic studies limit the scope of epidemiologic studies. Issues of timing with respect to latency and periods of breast vulnerability, and individual differences in susceptibility pose other challenges. Substantial work is needed in exposure assessment, toxicology, and susceptibility before we can expect a pay-off from large epidemiologic studies of breast cancer and environment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.