Evidence map›Paper›PMID 12824431›Full record

ArticleNucleic acids research2003

NORSp: Predictions of long regions without regular secondary structure.

Jinfeng Liu, Burkhard Rost

Abstract read
In one paragraph

Article in Nucleic acids research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Expose flexible conformations for intrinsically disordered protein.Current research in structural biology · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Intrinsically Disordered Proteins: An Overview.International journal of molecular sciences · 2022
    Review
  7. DISOselect: Disorder predictor selection at the protein level.Protein science : a publication of the Protein Society · 2020
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. A novel approach for predicting disordered regions in a protein sequence.Osong public health and research perspectives · 2014
    Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Understanding protein non-folding.Biochimica et biophysica acta · 2010
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jinfeng LiuCUBIC, Department of Biochemistry and Molecular Biophysics, Columbia University, 650 West 168th Street BB217, New York, NY 10032, USA.
Burkhard Rost

Funding

STRUCTURAL GENOMICS OF EUKARYOTIC MODEL ORGANISMSP50GM062413 · NIGMS · RUTGERS THE ST UNIV OF NJ NEW BRUNSWICK · PI MONTELIONE, GAETANO T · 2000 to 2004
$33.5M
Intruding into the midnight zone of protein comparisonsR01GM063029 · NIGMS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ROST, BURKHARD · 2001 to 2004
$1.1M
NIGMS NIH HHS 1-P50-GM62413-01NIGMS NIH HHS P50 GM062413NIGMS NIH HHS R01 GM063029NIGMS NIH HHS R01-GM63029-01
6 · The paper itself

Abstract

Many structurally flexible regions play important roles in biological processes. It has been shown that extended loopy regions are very abundant in the protein universe and that they have been conserved through evolution. Here, we present NORSp, a publicly available predictor for disordered regions in protein. Specifically, NORSp predicts long regions with NO Regular Secondary structure. Upon user submission of a protein sequence, NORSp will analyse the protein for its secondary structure, presence of transmembrane helices and coiled-coil. It will then return email to the user about the presence and position of disordered regions. NORSp can be accessed from http://cubic.bioc.columbia.edu/services/NORSp/.

Indexed as

SoftwareInternetProteinsProtein Structure, SecondarySequence Analysis, ProteinSoftware DesignUser-Computer InterfaceProteins

Identifiers

PMID12824431
PMCPMC168922

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.