Evidence map›Paper›PMID 12823650›Full record

Trial reportJournal of general internal medicine2003

Cost-effectiveness of a primary care depression intervention.

Jeffrey M Pyne, Kathryn M Rost, Mingliang Zhang, D Keith Williams, Jeffrey Smith, John Fortney

Abstract readClinical TrialMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of general internal medicine, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Collaborative care for depression and anxiety problems.The Cochrane database of systematic reviews · 2012
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Cost-Effectiveness of Collaborative Care for Depression in HIV Clinics.Journal of acquired immune deficiency syndromes (1999) · 2015
    Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Article
  14. Article
  15. Review
  16. Article
  17. [Cost effectiveness of a health insurance based case management programme for patients with affective disorders].Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2014
    Article
  18. Integrating mental health services into a general hospital in Puerto Rico.Journal of clinical psychology in medical settings · 2013
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Jeffrey M PyneHSRD Center for Mental Healthcare and Outcomes Research, Central Arkansas Veterans Healthcare System, Little Rock, Arkansas 72114-1706, USA. pynejeffreym@uams.edu
Kathryn M Rost
Mingliang Zhang
D Keith Williams
Jeffrey Smith
John Fortney

Funding

QUALITY IMPROVEMENT FOR DEPRESSIONR01MH054444 · NIMH · UNIVERSITY OF COLORADO DENVER · PI ROST, KATHRYN M · 1998 to 2002
$784k
DEPRESSION TREATMENT QUALITY INDICATORS FOR EMPLOYER USEK02MH063651 · NIMH · UNIVERSITY OF COLORADO DENVER · PI ROST, KATHRYN M · 2001 to 2005
$662k
MANAGED CARE AND ACCESS TO ALCOHOL TREATMENT SERVICESR01AA012085 · NIAAA · UNIVERSITY OF ARKANSAS MED SCIS LTL ROCK · PI FORTNEY, JOHN C · 1999 to 2000
$142k
DEPRESSION GUIDELINES--OUTCOMES AND COSTS OF CAREU01MH054444 · NIMH · UNIVERSITY OF ARKANSAS MED SCIS LTL ROCK · PI ROST, KATHRYN M · 1994 to 1996
–
NIAAA NIH HHS AA12085NIMH NIH HHS K02 MH063651NIMH NIH HHS MH54444NIMH NIH HHS MH63651NIMH NIH HHS R01 MH054444
6 · The paper itself

Abstract

objectiveTo determine the incremental cost-effectiveness of a quality improvement depression intervention (enhanced care) in primary care settings relative to usual care.

designFollowing stratification, we randomized 12 primary care practices to enhanced or usual care conditions and followed patients for 12 months.

settingPrimary care practices located in 10 states across the United States. PATIENTS/

participantsTwo hundred eleven patients beginning a new treatment episode for major depression.

interventionsTraining the primary care team to assess, educate, and monitor depressed patients during the acute and continuation stages of their depression treatment episode over 1 year. MEASUREMENTS AND MAIN

resultsCost-effectiveness was measured by calculating incremental (enhanced minus usual care) costs and quality-adjusted life years (QALYs) derived from SF-36 data. The mean incremental cost-effectiveness ratio in the main analysis was US dollars 15463 per QALY. The mean incremental cost-effectiveness ratios for the sensitivity analyses ranged from US dollars 11341 (using geographic block variables to control for pre-intervention service utilization) to US dollars 19976 (increasing the cost estimates by 50%) per QALY.

conclusionsThis quality improvement depression intervention was cost-effective relative to usual care compared to cost-effectiveness ratios for common primary care interventions and commonly cited cost-effectiveness ratio thresholds for intervention implementation.

Indexed as

Health Care CostsQuality-Adjusted Life YearsCost-Benefit AnalysisDepressionDepressive DisorderFemaleHealth Services ResearchHumansMalePrimary Health CareQuality Assurance, Health CareUnited States

Identifiers

PMID12823650
PMCPMC1494878

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.