ArticleWorld journal of surgery2003
Introducing new technologies: protecting subjects of surgical innovation and research.
Article in World journal of surgery, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Continuity of outcome assessment throughout the lifecycle of surgical research: mapping core outcome domains measured in early phase and late phase studies.BMC surgery · 2025Pooled it
- Pooled it
- Minimal Access in Pediatric Surgery: An Overview on Progress towards Dedicated Instrument Developments and Anesthesiologic Advances to Enhance Safe Completion of Procedures.Children (Basel, Switzerland) · 2024Article
- Article
- [Innovations in surgery-How can new technologies be safely implemented in the clinical practice?]Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2020Review
- Innovative Practice, Clinical Research, and the Ethical Advancement of Medicine.The American journal of bioethics : AJOB · 2019Article
- Bariatric surgery in class I obesity : a Position Statement from the International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO).Obesity surgery · 2014Article
- Surgical innovation as sui generis surgical research.Theoretical medicine and bioethics · 2013Article
- Promises and ethical pitfalls of surgical innovation: the case of bariatric surgery.Obesity surgery · 2013Review
- Innovation as the core strategy for the future success of academic health centres.Canadian journal of surgery. Journal canadien de chirurgie · 2011Article
- How should accredited specialists be trained to do new procedures?Annals of the Royal College of Surgeons of England · 2009Review
- FSH Injections and Ultrasonography Determine Presence of Ovarian Components in the Evaluation of Ovotesticular Disorders of Sex Development.International journal of pediatric endocrinology · 2009Article
- The ethics of using innovative therapies in the care of children.Paediatrics & child health · 2008Article
- Adoption of an innovation to repair aortic aneurysms at a Canadian hospital: a qualitative case study and evaluation.BMC health services research · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The system for protecting human research subjects is under increasing pressure. Under the currently dominant Regulatory Ethics Paradigm, clinical research protocols must be reviewed and approved by an institutional review board (IRB) or equivalent. Although the IRB was introduced into health care in part to protect patients and investigators from the inherent conflict between the best clinical interest of the individual patient and the interest of science and society in answering a clinical question, its rigorous standards and rigid framework discourage surgeons from seeking potentially valuable early IRB consultation. Most of the important advances in the history of medicine, such as anesthesia, appendectomy, antibiotics, intensive care, and immunization, were introduced through an informal, unregulated innovation process that has been enormously productive but can lead to ratification of ineffective or harmful treatment by credulous physicians and patients. We propose a surgical innovation ethics paradigm that is a more nimble, flexible source of institutional and public oversight and approval of innovations that are in the gray zone prior to their conversion to formal protocols that then require IRB approval. We also discuss the management of personal and institutional conflicts of interest.
Indexed as
Identifiers
12822049What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.