ArticleCell stress & chaperones2003
Molecular identification and expression of heat shock cognate 70 (hsc70) and heat shock protein 70 (hsp70) genes in the Pacific oyster Crassostrea gigas.
Article in Cell stress & chaperones, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 131 citations in OpenAlex.
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- Characterization of an inducible HSP70 gene in Chilo suppressalis and expression in response to environmental and biological stress.Cell stress & chaperones · 2020Article
- Description of strongly heat-inducible heat shock protein 70 transcripts from Baikal endemic amphipods.Scientific reports · 2019Article
- Corbicula fluminea gene expression modulated by CeOEnvironmental science and pollution research international · 2019Article
- Heat shock proteins in Varroa destructor exposed to heat stress and in-hive acaricides.Experimental & applied acarology · 2018Article
- The Role of the Cephalopod Digestive Gland in the Storage and Detoxification of Marine Pollutants.Frontiers in physiology · 2017Review
- Expression Characterization of Stress Genes Under High and Low Temperature Stresses in the Pacific Oyster, Crassostrea gigas.Marine biotechnology (New York, N.Y.) · 2016Article
- Cadmium Protection Strategies--A Hidden Trade-Off?International journal of molecular sciences · 2016Review
- Cloning and expression analysis of HSP70 gene from mangrove plant Kandelia obovata under cold stress.Ecotoxicology (London, England) · 2015Article
- Molecular cloning and expression of two heat-shock protein genes (HSC70/HSP70) from Prenant's schizothoracin (Schizothorax prenanti).Fish physiology and biochemistry · 2015Article
- In silico characterisation, homology modelling and structure-based functional annotation of blunt snout bream (Megalobrama amblycephala) Hsp70 and Hsc70 proteins.Journal of animal science and technology · 2015Article
- Identification of a novel cognate cytosolic Hsp70 gene (MnHsc70-2) from oriental river prawn Macrobrachium nipponense and comparison of its expressions with the first cognate Hsc70 (MnHsc70-1) under different stresses.Cell stress & chaperones · 2014Article
- Molecular characteristics of the HSP70 gene and its differential expression in female and male golden apple snails (Pomacea canaliculata) under temperature stimulation.Cell stress & chaperones · 2014Article
- Exposure to the neurotoxic dinoflagellate, Alexandrium catenella, induces apoptosis of the hemocytes of the oyster, Crassostrea gigas.Marine drugs · 2013Article
- Sequence analysis of a normalized cDNA library of Mytilus edulis hemocytes exposed to Vibrio splendidus LGP32 strain.Results in immunology · 2013Article
- Role of hypoxia-inducible factor α in response to hypoxia and heat shock in the Pacific oyster Crassostrea gigas.Marine biotechnology (New York, N.Y.) · 2012Article
- The involvement of HSP22 from bay scallop Argopecten irradians in response to heavy metal stress.Molecular biology reports · 2010Article
- Identification of a novel inducible cytosolic Hsp70 gene in Chinese shrimp Fenneropenaeus chinensis and comparison of its expression with the cognate Hsc70 under different stresses.Cell stress & chaperones · 2010Article
- Transcriptional expression levels of cell stress marker genes in the Pacific oyster Crassostrea gigas exposed to acute thermal stress.Cell stress & chaperones · 2009Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The 70-kDa heat shock protein (Hsp) family is composed of both environmentally inducible (Hsp) and constitutively expressed (Hsc) family members. We sequenced 2 genes encoding an Hsp70 and an Hsc70 in the Pacific oyster Crassostrea gigas. The Cghsc70 gene contained introns, whereas the Cghsp70 gene did not. Moreover, the corresponding amino acid sequences of the 2 genes presented all the characteristic motifs of the Hsp70 family. We also investigated the expression of Hsp70 in tissues of oysters experimentally exposed to metal. A recombinant Hsc72 was used as an antigen to produce a polyclonal antibody to quantify soluble Hsp70 by enzyme-linked immunosorbent assay in protein samples extracted from oysters. Our results showed that metals (copper and cadmium) induced a decrease in cytosolic Hsp70 level in gills and digestive gland of oysters experimentally exposed to metal. These data suggest that metals may inhibit stress protein synthesis.
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