ArticleGenome research2003
Antisense transcripts with FANTOM2 clone set and their implications for gene regulation.
Article in Genome research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers.
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Who cites it
100 citing papers in PubMed.
- A transcriptome-wide systematic search does not detect A-to-I RNA editing inGenome research · 2026Article
- Natural antisense transcripts as versatile regulators of gene expression.Nature reviews. Genetics · 2024Review
- Interdependent Transcription of a Natural Sense/Antisense Transcripts Pair (Non-coding RNA · 2022Article
- Non-coding antisense transcripts: fine regulation of gene expression in cancer.Computational and structural biotechnology journal · 2022Review
- Endogenous Double-Stranded RNA.Non-coding RNA · 2021Review
- Genetic compensation: A phenomenon in search of mechanisms.PLoS genetics · 2017Review
- Normalized long read RNA sequencing in chicken reveals transcriptome complexity similar to human.BMC genomics · 2017Article
- Massive Effect on LncRNAs in Human Monocytes During Fungal and Bacterial Infections and in Response to Vitamins A and D.Scientific reports · 2017Article
- Natural Antisense Transcripts at the Interface between Host Genome and Mobile Genetic Elements.Frontiers in microbiology · 2017Article
- Article
- Article
- Paradigm shifts in genomics through the FANTOM projects.Mammalian genome : official journal of the International Mammalian Genome Society · 2015Article
- Detection of natural antisense non-coding RNAs transcribed fromBiomedical reports · 2015Article
- Transpositional shuffling and quality control in male germ cells to enhance evolution of complex organisms.Annals of the New York Academy of Sciences · 2015Article
- Review
- Development of genodynamic metrics for exploring the biophysics of DNA polymorphisms.Journal of computational biology and bioinformatics research · 2014Article
- Examining the condition-specific antisense transcription in S. cerevisiae and S. paradoxus.BMC genomics · 2014Article
- Contribution of natural antisense transcription to an endogenous siRNA signature in human cells.BMC genomics · 2014Article
- Guided by RNAs: X-inactivation as a model for lncRNA function.Journal of molecular biology · 2013Review
- A rice cis-natural antisense RNA acts as a translational enhancer for its cognate mRNA and contributes to phosphate homeostasis and plant fitness.The Plant cell · 2013Article
40 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have used the FANTOM2 mouse cDNA set (60,770 clones), public mRNA data, and mouse genome sequence data to identify 2481 pairs of sense-antisense transcripts and 899 further pairs of nonantisense bidirectional transcription based upon genomic mapping. The analysis greatly expands the number of known examples of sense-antisense transcript and nonantisense bidirectional transcription pairs in mammals. The FANTOM2 cDNA set appears to contain substantially large numbers of noncoding transcripts suitable for antisense transcript analysis. The average proportion of loci encoding sense-antisense transcript and nonantisense bidirectional transcription pairs on autosomes was 15.1 and 5.4%, respectively. Those on the X chromosome were 6.3 and 4.2%, respectively. Sense-antisense transcript pairs, rather than nonantisense bidirectional transcription pairs, may be less prevalent on the X chromosome, possibly due to X chromosome inactivation. Sense and antisense transcripts tended to be isolated from the same libraries, where nonantisense bidirectional transcription pairs were not apparently coregulated. The existence of large numbers of natural antisense transcripts implies that the regulation of gene expression by antisense transcripts is more common that previously recognized. The viewer showing mapping patterns of sense-antisense transcript pairs and nonantisense bidirectional transcription pairs on the genome and other related statistical data is available on our Web site.
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