Evidence map›Paper›PMID 12817999›Full record

ArticleBreast cancer research : BCR2003

Risk factors for breast cancer in a population with high incidence rates.

Margaret Wrensch, Terri Chew, Georgianna Farren, Janice Barlow, Flavia Belli, Christina Clarke, Christine A Erdmann, Marion Lee, Michelle Moghadassi, Roni Peskin-Mentzer and 5 more

Open access · goldAbstract read
In one paragraph

Article in Breast cancer research : BCR, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  6. Article
  7. Residential mobility and breast cancer in Marin County, California, USA.International journal of environmental research and public health · 2013
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  15. Influence of nativity status on breast cancer risk among US black women.Journal of urban health : bulletin of the New York Academy of Medicine · 2006
    Article
  16. Article
  17. Breast cancer in Marin County.Breast cancer research : BCR · 2003
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Margaret WrenschUniversity of California, San Francisco, California, USA. wrensch@itsa.ucsf.edu
Terri Chew
Georgianna Farren
Janice Barlow
Flavia Belli
Christina Clarke
Christine A Erdmann
Marion Lee
Michelle Moghadassi
Roni Peskin-Mentzer
Charles P Quesenberry
Virginia Souders-Mason
Linda Spence
Marisa Suzuki
Mary Gould
University of California, San Francisco · USZero Breast Cancer · USRafael Advanced Defense Systems (Israel) · ILKaiser Foundation Hospital · USLawrence Berkeley National Laboratory · USNorthern California Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis report examines generally recognized breast cancer risk factors and years of residence in Marin County, California, an area with high breast cancer incidence and mortality rates.

methodsEligible women who were residents of Marin County diagnosed with breast cancer in 1997-99 and women without breast cancer obtained through random digit dialing, frequency-matched by cases' age at diagnosis and ethnicity, participated in either full in-person or abbreviated telephone interviews.

resultsIn multivariate analyses, 285 cases were statistically significantly more likely than 286 controls to report being premenopausal, never to have used birth control pills, a lower highest lifetime body mass index, four or more mammograms in 1990-94, beginning drinking after the age of 21, on average drinking two or more drinks per day, the highest quartile of pack-years of cigarette smoking and having been raised in an organized religion. Cases and controls did not significantly differ with regard to having a first-degree relative with breast cancer, a history of benign breast biopsy, previous radiation treatment, age at menarche, parity, use of hormone replacement therapy, age of first living in Marin County, or total years lived in Marin County. Results for several factors differed for women aged under 50 years or 50 years and over.

conclusionsDespite similar distributions of several known breast cancer risk factors, case-control differences in alcohol consumption suggest that risk in this high-risk population might be modifiable. Intensive study of this or other areas of similarly high incidence might reveal other important risk factors proximate to diagnosis.

Indexed as

Alcohol DrinkingBreast NeoplasmsCaliforniaCase-Control StudiesFemaleHumansIncidenceMiddle AgedMultivariate AnalysisReligionRisk FactorsSmokingSocioeconomic FactorsTime Factors

Identifiers

PMID12817999
PMCPMC165017
OpenAlexW1818165656

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.