ReviewBreast cancer research : BCR2003
Nuclear localization and function of polypeptide ligands and their receptors: a new paradigm for hormone specificity within the mammary gland?
Review in Breast cancer research : BCR, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 37 citations in OpenAlex.
- Estradiol, progesterone and prolactin modulate mammary gland morphogenesis in adult female plains vizcacha (Lagostomus maximus).Journal of molecular histology · 2013Article
- Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor family.Cell & bioscience · 2012Article
- TM-25659 enhances osteogenic differentiation and suppresses adipogenic differentiation by modulating the transcriptional co-activator TAZ.British journal of pharmacology · 2012Article
- Association of insulin-like growth factor 2 with the insulin-linked polymorphic region in cultured fetal thymus cells.Biochemistry · 2009Article
- Rational design of competitive prolactin/growth hormone receptor antagonists.Journal of mammary gland biology and neoplasia · 2008Review
- JAK-STAT pathway in carcinogenesis: is it relevant to cholangiocarcinoma progression?World journal of gastroenterology · 2007Review
- The phosphoinositide kinase PIKfyve mediates epidermal growth factor receptor trafficking to the nucleus.Cancer research · 2007Article
- Proteasomes mediate prolactin-induced receptor down-regulation and fragment generation in breast cancer cells.The Journal of biological chemistry · 2005Article
- Roles and regulation of stat family transcription factors in human breast cancer.The American journal of pathology · 2004Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The specific effects triggered by polypeptide hormone/growth factor stimulation of mammary cells were considered mediated solely by receptor-associated signaling networks. A compelling body of new data, however, clearly indicates that polypeptide ligands and/or their receptors are transported into the nucleus, where they function directly to regulate the expression of specific transcription factors and gene loci. The intranuclear function of these complexes may contribute to the explicit functions associated with a given ligand, and may serve as new targets for pharmacologic intervention.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.