Evidence map›Paper›PMID 12814456›Full record

ArticleBritish journal of clinical pharmacology2003

Evidence for an age and gender bias in the secondary prevention of ischaemic heart disease in primary care.

David Williams, Kathleen Bennett, John Feely

Open access · bronzeAbstract read
In one paragraph

Article in British journal of clinical pharmacology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
21.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 101 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
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  5. Article
  6. Ageism directed to older adults in health services: A scoping review.Revista latino-americana de enfermagem · 2023
    Article
  7. Observational
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  11. Review
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  16. Age equity in different models of primary care practice in Ontario.Canadian family physician Medecin de famille canadien · 2011
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

David WilliamsDepartment of Clinical Pharmacology, Aberdeen Royal Infirmary, Aberdeen, UK. david.j.williams@arh.grampian.scot.nhs.uk
Kathleen Bennett
John Feely
St. James's Hospital · IEAberdeen Royal Infirmary · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo determine if a gender or age bias exists in the prescription of important secondary preventive therapies for ischaemic heart disease in primary care.

methodsWe identified 15 590 patients with ischaemic heart disease on the basis that they received a prescription for nitrate therapy over a 1-year period (September 1999 to August 2000) from the Eastern Region of the General Medical Services scheme in Ireland (population of 334 031), which provides free health service to those eligible patients in primary care. Odds ratios (OR) for the prescription of aspirin, beta-blockers, statins, calcium channel antagonists and ACE inhibitors in women and in those aged> 65 years were determined.

resultsFemale patients were less likely to receive a prescription for a beta-blocker [OR = 0.84, 95% confidence interval (CI) = 0.79, 0.89, P < 0.001], aspirin (OR = 0.72, 95% CI = 0.67, 0.78, P < 0.001), and ACE inhibitors (OR = 0.83, 95% CI = 0.78, 0.89, P < 0.001) compared with their male counterparts. However, women were more likely to receive anxiolytic benzodiazepines (OR = 1.71, 95% CI = 1.59, 1.85, P < 0.001) compared with their male counterparts. Elderly patients (aged> 65 years) were less likely to receive aspirin (OR = 0.92, 95% CI = 0.85, 0.99, P < 0.001), beta-blocker (OR = 0.66, 95% CI = 0.62, 0.71, P < 0.001) and a statin (OR = 0.5, 95% CI = 0.46, 0.53, P < 0.001).

conclusionsAn age and gender bias exists in the prescription of important secondary preventive therapies in primary care that may lead to increased mortality from ischaemic heart disease in these groups.

Indexed as

Adrenergic beta-AntagonistsAgedAge FactorsAngiotensin-Converting Enzyme InhibitorsAspirinBiasCalcium Channel BlockersCardiotonic AgentsFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMyocardial IschemiaNitratesOdds RatioPlatelet Aggregation InhibitorsAdrenergic beta-AntagonistsAngiotensin-Converting Enzyme InhibitorsAspirinCalcium Channel BlockersCardiotonic AgentsHydroxymethylglutaryl-CoA Reductase InhibitorsNitratesPlatelet Aggregation Inhibitors

Identifiers

PMID12814456
PMCPMC1884265
OpenAlexW1962264436

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.