ArticleThe Biochemical journal2003
Effect of a null mutation of the oviduct-specific glycoprotein gene on mouse fertilization.
Article in The Biochemical journal, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 55 citations in OpenAlex.
- Three Novel Mutations in TUBB8 Cause Female Infertility Due to Multiple Morphological Abnormalities of the Oocyte and Early Embryo.Reproductive sciences (Thousand Oaks, Calif.) · 2025Article
- Molecular Evolution of theAnimals : an open access journal from MDPI · 2024Article
- The fluid factor OVGP1 provides a significant oviductal microenvironment for the reproductive process in golden hamster†.Biology of reproduction · 2024Article
- The physiological and pathological mechanisms of early embryonic development.Fundamental research · 2022Review
- Mysteries and unsolved problems of mammalian fertilization and related topics.Biology of reproduction · 2022Review
- The role of oviduct-specific glycoprotein (OVGP1) in modulating biological functions of gametes and embryos.Histochemistry and cell biology · 2022Review
- Chitinases and Chitinase-Like Proteins as Therapeutic Targets in Inflammatory Diseases, with a Special Focus on Inflammatory Bowel Diseases.International journal of molecular sciences · 2021Review
- New Insights into the Mammalian Egg Zona Pellucida.International journal of molecular sciences · 2021Review
- A Comparative View on the Oviductal Environment during the Periconception Period.Biomolecules · 2020Review
- Roles of steroid hormones in oviductal functionReproduction (Cambridge, England) · 2020Review
- Genes Encoding Mammalian Oviductal Proteins Involved in Fertilization are Subjected to Gene Death and Positive Selection.Journal of molecular evolution · 2018Article
- Effects of recombinant OVGP1 protein on in vitro bovine embryo development.The Journal of reproduction and development · 2018Article
- Oviductal glycoprotein 1 (OVGP1) is expressed by endometrial epithelium that regulates receptivity and trophoblast adhesion.Journal of assisted reproduction and genetics · 2018Article
- Review: The epic journey of sperm through the female reproductive tract.Animal : an international journal of animal bioscience · 2018Review
- Review
- Extra-oviductal expression of oviductal glycoprotein 1 in mouse: Detection in testis, epididymis and ovary.Journal of biosciences · 2017Article
- Recombinant hamster oviductin is biologically active and exerts positive effects on sperm functions and sperm-oocyte binding.PloS one · 2015Article
- Characterization of a diverse secretome generated by the mouse preimplantation embryo in vitro.Reproductive biology and endocrinology : RB&E · 2010Article
- Mouse oviduct-specific glycoprotein is an egg-associated ZP3-independent sperm-adhesion ligand.Journal of cell science · 2009Article
- Reassessing the role of protein-carbohydrate complementarity during sperm-egg interactions in the mouse.The International journal of developmental biology · 2008Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mammalian fertilization process takes place in a complex microenvironment within the female genital tract. A member of the chitinase protein family, oviduct-specific glycoprotein (OGP), has been identified in oviductal fluid from various mammalian species, including humans. Although OGP is widely believed to be involved in the process of mammalian fertilization, including spermatozoon function and gamete interactions, based on experimental results obtained in vitro, its physiological significance remains controversial. The present study established OGP gene-null ( ogp (-/-)) mice, and primarily characterized their reproductive properties to study the physiological function(s) of OGP. Results obtained from studies using an in vivo or in vitro system showed that the fertility of ogp (-/-) females was within normal limits. These results indicate that OGP is not essential for the process of in vivo fertilization, at least in mice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.