ArticleJournal of bacteriology2003
Identification and mutational analysis of bacteriophage PRD1 holin protein P35.
Article in Journal of bacteriology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 42 citations in OpenAlex.
- Antibacterial Potential of Non-Tailed Icosahedral Phages Alone and in Combination with Antibiotics.Current microbiology · 2024Article
- Cloning and Characterization of a Thermostable Endolysin of Bacteriophage TP-84 as a Potential Disinfectant and Biofilm-Removing Biological Agent.International journal of molecular sciences · 2022Article
- Chronic Release of Tailless Phage Particles from Lactococcus lactis.Applied and environmental microbiology · 2022Article
- Unraveling Protein Interactions between the Temperate Virus Bam35 and ItsInternational journal of molecular sciences · 2021Article
- Half a Century of Research on Membrane-Containing Bacteriophages: Bringing New Concepts to Modern Virology.Viruses · 2019Review
- Phage lysis: three steps, three choices, one outcome.Journal of microbiology (Seoul, Korea) · 2014Review
- Reliability of nine programs of topological predictions and their application to integral membrane channel and carrier proteins.Journal of molecular microbiology and biotechnology · 2014Article
- Phage lysis: do we have the hole story yet?Current opinion in microbiology · 2013Review
- Visualization of pinholin lesions in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Functional analysis of a class I holin, P2 Y.Journal of bacteriology · 2013Article
- Characterization and determination of holin protein of Streptococcus suis bacteriophage SMP in heterologous host.Virology journal · 2012Article
- Micron-scale holes terminate the phage infection cycle.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Evolutionary dominance of holin lysis systems derives from superior genetic malleability.Microbiology (Reading, England) · 2008Article
- The pinholin of lambdoid phage 21: control of lysis by membrane depolarization.Journal of bacteriology · 2007Article
- Genome characterization of lipid-containing marine bacteriophage PM2 by transposon insertion mutagenesis.Journal of virology · 2006Article
- Global changes in cellular gene expression during bacteriophage PRD1 infection.Journal of virology · 2006Article
- The Holin protein of bacteriophage PRD1 forms a pore for small-molecule and endolysin translocation.Journal of bacteriology · 2005Article
- The linear double-stranded DNA of phage Bam35 enters lysogenic host cells, but the late phage functions are suppressed.Journal of bacteriology · 2005Article
- Identification of a holin encoded by the Streptomyces aureofaciens phage micro1/6; functional analysis in Escherichia coli system.Folia microbiologica · 2004Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Holin proteins are phage-induced integral membrane proteins which regulate the access of lytic enzymes to host cell peptidoglycan at the time of release of progeny viruses by host cell lysis. We describe the identification of the membrane-containing phage PRD1 holin gene (gene XXXV). The PRD1 holin protein (P35, 12.8 kDa) acts similarly to its functional counterpart from phage lambda (gene S), and the defect in PRD1 gene XXXV can be corrected by the presence of gene S of lambda. Several nonsense, missense, and insertion mutations in PRD1 gene XXXV were analyzed. These studies support the overall conclusion that the charged amino acids at the protein C terminus are involved in the timing of host cell lysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.