ArticleThe British journal of ophthalmology2003
Visual loss in uveitis of childhood.
Article in The British journal of ophthalmology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
74 citing papers in PubMed, 1 synthesis or guideline pooled it, 296 citations in OpenAlex.
- Evidence-based, interdisciplinary guidelines for anti-inflammatory treatment of uveitis associated with juvenile idiopathic arthritis.Rheumatology international · 2012Guideline
- [Trabeculectomy in uveitis associated with juvenile idiopathic arthritis: long-term results in pediatric secondary glaucoma].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2014Trial
- Trial
- Systemic immunosuppressive therapy in juvenile idiopathic arthritis-associated uveitis.International ophthalmology · 2026Article
- Novel advances in juvenile idiopathic arthritis associated uveitis.Arthritis research & therapy · 2026Review
- Changing paediatric uveitis patterns in Italy: an eight-year experience from the Reggio Emilia Uveitis clinic.International ophthalmology · 2026Article
- The effect of anti-TNF α therapy on refractory non-infectious pediatric uveitis in Saudi Arabia.BMC ophthalmology · 2026Article
- Implications of peripapillary retinal nerve fiber layer thickening by optical coherence tomography in children with pars planitis.Journal of ophthalmic inflammation and infection · 2025Article
- Candidate Tear-Based Uveitis Biomarkers in Children with JIA Based on Arthritis Activity and Topical Corticosteroid Use.Ocular immunology and inflammation · 2025Article
- Impact of socioeconomic factors on cardiovascular diseases, diabetes and all-cause mortality in patients with uveitis: a Danish cohort study.BMJ public health · 2025Article
- Demography in Swiss paediatric uveitis: a retrospective cohort study.Journal of ophthalmic inflammation and infection · 2024Article
- Safety and efficacy of intravitreal dexamethasone implantation along with phacoemulsification and intraocular lens implantation in children with uveitis.Journal of ophthalmic inflammation and infection · 2024Article
- Paediatric Uveitis - the uniqueness in clinical presentation and the efficacy of biologics treatment.Journal of ophthalmic inflammation and infection · 2024Article
- Prevalence and clinical characteristics of uveitic glaucoma: multicentric study in Bogotá, Colombia.Eye (London, England) · 2024Article
- Recurrent and chronic anterior uveitis: Long-term outcome and treatment strategies.Indian journal of ophthalmology · 2024Article
- Monitoring compliance to topical therapy in children and young people with uveitis.Eye (London, England) · 2024Article
- Establishing the Normative Data Set Necessary for Imaging-Based Childhood Uveitis Surveillance: A Cross-Sectional Study.Investigative ophthalmology & visual science · 2024Observational
- Diagnosis and Management of Non-Infectious Uveitis in Pediatric Patients.Paediatric drugs · 2024Review
- A clearer vision: insights into juvenile idiopathic arthritis-associated uveitis.Proceedings (Baylor University. Medical Center) · 2024Article
- Pediatric Uveitis in a Tertiary Referral Center in East China: Clinical Patterns and Visual Outcomes.Journal of ophthalmology · 2024Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo investigate the manifestations and severity of uveitis in children and to identify the risk and specific causes of blindness in this population.
methodsRetrospective study of data of 123 consecutive patients examined with active uveitis and the onset of ocular disease before the age of 16 years. Numerous variables were assessed including age and sex distribution, laboratory data, the presence of systemic diseases, onset and course of ocular inflammation, clinical features and complications, therapeutic strategies and their outcomes, final visual acuity, and characteristics associated with poor visual outcome.
resultsSystemic disease was observed in 36/123 patients (29%), with juvenile idiopathic arthritis being the most frequent (25/123, 20%). Toxoplasma retinochoroiditis was diagnosed in 12/23 patients with posterior uveitis (52%; 10% of all with uveitis). Severe intraocular inflammation required systemic drugs in 57 (46%) patients. Ocular complications were observed in 93 patients (76%), of which the most common was cataract (43/123, 35%). Intraocular surgery was required in 35 patients (28%; in total 75 procedures). Three patients (2%) became legally blind and an additional 20/121 (17%) had one legally blind eye caused by uveitis. The most frequent causes of blindness were chorioretinal scars in the macular area and glaucoma in contrast with cystoid macular oedema (CMO) in adults.
conclusionsUveitis in childhood is a potentially blinding disease, in the majority of patients characterised by a chronic course and a high complication rate.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.