ArticleGenetics2003
Repair of damaged and mismatched DNA by the XPC homologues Rhp41 and Rhp42 of fission yeast.
Article in Genetics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- CSB-independent, XPC-dependent transcription-coupled repair inProceedings of the National Academy of Sciences of the United States of America · 2022Article
- DNA Repair in Haploid Context.International journal of molecular sciences · 2021Review
- Characterization of Alternaria infectoria extracellular vesicles.Medical mycology · 2014Article
- Atl1 regulates choice between global genome and transcription-coupled repair of O(6)-alkylguanines.Molecular cell · 2012Article
- Cassette series designed for live-cell imaging of proteins and high-resolution techniques in yeast.Yeast (Chichester, England) · 2012Article
- Small epitope-linker modules for PCR-based C-terminal tagging in Saccharomyces cerevisiae.Yeast (Chichester, England) · 2009Article
- Complementary roles of yeast Rad4p and Rad34p in nucleotide excision repair of active and inactive rRNA gene chromatin.Molecular and cellular biology · 2008Article
- Brc1-mediated rescue of Smc5/6 deficiency: requirement for multiple nucleases and a novel Rad18 function.Genetics · 2007Article
- Biochemical and structural domain analysis of xeroderma pigmentosum complementation group C protein.Biochemistry · 2006Article
- Ddb1 controls genome stability and meiosis in fission yeast.Genes & development · 2005Article
- Short-patch correction of C/C mismatches in human cells.Nucleic acids research · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rhp41 and Rhp42 of Schizosaccharomyces pombe are homologues of human XPC, which is involved in nucleotide excision repair (NER) of damaged DNA. Inactivation of rhp41 caused moderate sensitivity to ultraviolet (UV) radiation. In addition, an increase of mitotic mutation rates was observed in the rhp41 mutant, which was dependent on active translesion polymerase Z. UV sensitivity and mutation rates were not different between rhp42 and wild type, but compared to rhp41 were further increased in rhp41 rhp42 cells. Transcription of the fbp1 gene (induced in vegetative cells) and of the SPBC1289.14 gene (induced during meiosis) was strongly blocked by UV-induced damages in the rhp41 mutant, but not, or only slightly, reduced in rhp42 background. NER-dependent short-patch repair of mismatches formed during meiosis was slightly affected in rhp41, moderately affected in rhp42, and absent in rhp41 rhp42. Epistasis analysis with rhp7 and rhp26 indicates that Rhp41 and Rhp42 are both involved in the global genome and transcription-coupled repair subpathways of NER. Rhp41 plays a major role in damage repair and Rhp42 in mismatch repair.
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Registered trials
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