ArticlePlant physiology2003
Enhancer trapping reveals widespread circadian clock transcriptional control in Arabidopsis.
Article in Plant physiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
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Who cites it
78 citing papers in PubMed, 176 citations in OpenAlex.
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- Clocking out and letting go to unleash green biotech applications in a photosynthetic host.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Characterizing the circadian connectome of Ocimum tenuiflorum using an integrated network theoretic framework.Scientific reports · 2023Article
- Periodicity and Spectral Composition of Light in the Regulation of Hypocotyl Elongation of Sunflower Seedlings.Plants (Basel, Switzerland) · 2022Article
- Experimental Design for Time-Series RNA-Seq Analysis of Gene Expression and Alternative Splicing.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Open chromatin in grapevine marks candidate CREs and with other chromatin features correlates with gene expression.The Plant journal : for cell and molecular biology · 2021Article
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- The diverse and unanticipated roles of histone deacetylase 9 in coordinating plant development and environmental acclimation.Journal of experimental botany · 2020Review
- The Plant Circadian Oscillator.Biology · 2019Review
- Widespread inter-individual gene expression variability inMolecular systems biology · 2019Article
- TheFrontiers in plant science · 2019Article
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- Beyond Transcription: Fine-Tuning of Circadian Timekeeping by Post-Transcriptional Regulation.Genes · 2018Review
- ZINC-FINGER interactions mediate transcriptional regulation of hypocotyl growth inProceedings of the National Academy of Sciences of the United States of America · 2018Article
- Identification of Leaf Promoters for Use in Transgenic Wheat.Plants (Basel, Switzerland) · 2018Article
- Article
- Daily rhythmicity in coastal microbial mats.NPJ biofilms and microbiomes · 2018Article
- Adaptation of iCLIP to plants determines the binding landscape of the clock-regulated RNA-binding protein AtGRP7.Genome biology · 2017Article
- A novel role of the soybean clock gene LUX ARRHYTHMO in male reproductive development.Scientific reports · 2017Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The circadian clock synchronizes the internal biology of an organism with the environment and has been shown to be widespread among organisms. Microarray experiments have shown that the circadian clock regulates mRNA abundance of about 10% of the transcriptome in plants, invertebrates, and mammals. In contrast, the circadian clock regulates the transcription of the virtually all cyanobacterial genes. To determine the extent to which the circadian clock controls transcription in Arabidopsis, we used in vivo enhancer trapping. We found that 36% of our enhancer trap lines display circadian-regulated transcription, which is much higher than estimates of circadian regulation based on analysis of steady-state mRNA abundance. Individual lines identified by enhancer trapping exhibit peak transcription rates at circadian phases spanning the complete circadian cycle. Flanking genomic sequence was identified for 23 enhancer trap lines to identify clock-controlled genes (CCG-ETs). Promoter analysis of CCG-ETs failed to predict new circadian clock response elements (CCREs), although previously defined CCREs, the CCA1-binding site, and the evening element were identified. However, many CCGs lack either the CCA1-binding site or the evening element; therefore, the presence of these CCREs is insufficient to confer circadian regulation, and it is clear that additional elements play critical roles.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.