ArticlePlant physiology2003
Transcriptome profiling of sulfur-responsive genes in Arabidopsis reveals global effects of sulfur nutrition on multiple metabolic pathways.
Article in Plant physiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers.
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Who cites it
116 citing papers in PubMed, 301 citations in OpenAlex.
- Hidden players in plant response to sulfur deficit and beyond: insights into the function of the proteins Sulfur Deficiency Induced and Response to Low Sulfur.Journal of experimental botany · 2026Review
- Identification and characterization of low-sulfur-inducible genes and pathways in roots of upland and lowland rice grown under hydroponic and soil conditions.Journal of experimental botany · 2026Article
- Circadian clock-related transcription factors Reveille 1 and Reveille 8 regulate the O-acetylserine cluster genes and sulfur homeostasis.Plant physiology · 2026Article
- Sulfate starvation response modules connect sulfur metabolism to photorespiration and photosynthesis.The Plant journal : for cell and molecular biology · 2026Article
- An atlas of plant selenium metabolism.The New phytologist · 2026Review
- Differential expression of sulfate transporters under selenium supply identifies OsSULTR1;1 as a candidate for nutritional enhancement in super basmati rice.Molecular biology reports · 2026Article
- Increased anthocyanin accumulation and plant growth by driving PAP1 expression using the 3'downstream region of the sulfate transporter SULTR2;1 gene.Plant molecular biology · 2026Article
- Article
- Short coiled-coil proteins from plants and metazoans - the 'jacks of all trades'.The FEBS journal · 2025Review
- Sulfate Deficiency-Responsive MicroRNAs in Tomato Uncover an Expanded and Functionally Integrated Regulatory Network.International journal of molecular sciences · 2025Article
- Genome-Wide Identification of the Sulfate Transporter Gene Family Reveals ThatAntioxidants (Basel, Switzerland) · 2025Article
- Sulfate Availability and Hormonal Signaling in the Coordination of Plant Growth and Development.International journal of molecular sciences · 2024Review
- Root-based inorganic carbon uptake increases the growth ofFrontiers in plant science · 2024Article
- Autophagy and multivesicular body pathways cooperate to protect sulfur assimilation and chloroplast functions.Plant physiology · 2023Article
- The molecular mechanism of microRNA duplex selectivity of Arabidopsis ARGONAUTE10.Nucleic acids research · 2022Article
- Evolutionary and Gene Expression Analyses Reveal New Insights into the Role ofPlants (Basel, Switzerland) · 2022Article
- Local and Systemic Response to Heterogeneous Sulfate Resupply after Sulfur Deficiency in Rice.International journal of molecular sciences · 2022Article
- Sulfur Stable Isotope Discrimination in Rice: A Sulfur Isotope Mass Balance Study.Frontiers in plant science · 2022Article
- Retrograde sulfur flow from glucosinolates to cysteine inProceedings of the National Academy of Sciences of the United States of America · 2021Article
- Metabolism and Regulatory Functions ofFrontiers in plant science · 2021Review
56 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sulfate is a macronutrient required for cell growth and development. Arabidopsis has two high-affinity sulfate transporters (SULTR1;1 and SULTR1;2) that represent the sulfate uptake activities at the root surface. Sulfur limitation (-S) response relevant to the function of SULTR1;2 was elucidated in this study. We have isolated a novel T-DNA insertion allele defective in the SULTR1;2 sulfate transporter. This mutant, sel1-10, is allelic with the sel1 mutants identified previously in a screen for increased tolerance to selenate, a toxic analog of sulfate (Shibagaki et al., 2002). The abundance of SULTR1;1 mRNA was significantly increased in the sel1-10 mutant; however, this compensatory up-regulation of SULTR1;1 was not sufficient to restore the growth. The sulfate content of the mutant was 10% to 20% of the wild type, suggesting that induction of SULTR1;1 is not fully complementing the function of SULTR1;2 and that SULTR1;2 serves as the major facilitator for the acquisition of sulfate in Arabidopsis roots. Transcriptome analysis of approximately 8,000 Arabidopsis genes in the sel1-10 mutant suggested that dysfunction of the SULTR1;2 transporter can mimic general -S symptoms. Hierarchal clustering of sulfur responsive genes in the wild type and mutant indicated that sulfate uptake, reductive sulfur assimilation, and turnover of secondary sulfur metabolites are activated under -S. The profiles of -S-responsive genes further suggested induction of genes that may alleviate oxidative damage and generation of reactive oxygen species caused by shortage of glutathione.
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