ArticleThe EMBO journal2003
Three-dimensional structure of the M-MuLV CA protein on a lipid monolayer: a general model for retroviral capsid assembly.
Article in The EMBO journal, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed, 64 citations in OpenAlex.
- Spontaneous non-canonical assembly of CcmK hexameric components from β-carboxysome shells of cyanobacteria.PloS one · 2017Article
- The N-terminus of murine leukaemia virus p12 protein is required for mature core stability.PLoS pathogens · 2014Article
- Contribution of glutamine residues in the helix 4-5 loop to capsid-capsid interactions in simian immunodeficiency virus of macaques.Journal of virology · 2014Article
- Unclosed HIV-1 capsids suggest a curled sheet model of assembly.Journal of molecular biology · 2013Article
- Lipid monolayer and sparse matrix screening for growing two-dimensional crystals for electron crystallography: methods and examples.Methods in molecular biology (Clifton, N.J.) · 2013Article
- Characterization of a monoclonal anti-capsid antibody that cross-reacts with three major primate lentivirus lineages.Virology · 2012Article
- Bromovirus RNA replication compartment formation requires concerted action of 1a's self-interacting RNA capping and helicase domains.Journal of virology · 2012Article
- Solution properties of murine leukemia virus gag protein: differences from HIV-1 gag.Journal of virology · 2011Article
- Ordered assembly of murine leukemia virus capsid protein on lipid nanotubes directs specific binding by the restriction factor, Fv1.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- 3D visualization of HIV virions by cryoelectron tomography.Methods in enzymology · 2010Article
- Two-dimensional crystals of carboxysome shell proteins recapitulate the hexagonal packing of three-dimensional crystals.Protein science : a publication of the Protein Society · 2009Article
- Retroviral capsid assembly: a role for the CA dimer in initiation.Journal of molecular biology · 2009Article
- Article
- Mutations in the spacer peptide and adjoining sequences in Rous sarcoma virus Gag lead to tubular budding.Journal of virology · 2008Article
- Cooperative role of the MHR and the CA dimerization helix in the maturation of the functional retrovirus capsid.Virology · 2008Article
- Critical role of conserved hydrophobic residues within the major homology region in mature retroviral capsid assembly.Journal of virology · 2008Article
- Insulin-like growth factor II mRNA binding protein 1 associates with Gag protein of human immunodeficiency virus type 1, and its overexpression affects virus assembly.Journal of virology · 2008Article
- A molecular switch required for retrovirus assembly participates in the hexagonal immature lattice.The EMBO journal · 2008Article
- RSV capsid polymorphism correlates with polymerization efficiency and envelope glycoprotein content: implications that nucleation controls morphogenesis.Journal of molecular biology · 2008Article
- Irregular and Semi-Regular Polyhedral Models for Rous Sarcoma Virus Cores.Computational and mathematical methods in medicine · 2008Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although retroviruses from different genera form morphologically distinct capsids, we have proposed that all of these structures are composed of similar hexameric arrays of capsid (CA) protein subunits and that their distinct morphologies reflect different distributions of pentameric declinations that allow the structures to close. Consistent with this model, CA proteins from both HIV-1 and Rous sarcoma virus (RSV) form similar hexagonal lattices. However, recent structural studies have suggested that the Moloney murine leukemia virus (M-MuLV) CA protein may assemble differently. We now report an independent three-dimensional reconstruction of two-dimensional crystals of M-MuLV CA. This new reconstruction reveals a hexameric lattice that is similar to those formed by HIV-1 and RSV CA, supporting a generalized model for retroviral capsid assembly.
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