SynthesisThe Cochrane database of systematic reviews2003
Heparin for pregnant women with acquired or inherited thrombophilias.
Synthesis in The Cochrane database of systematic reviews, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 6 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Venous thromboembolism prophylaxis for women at risk during pregnancy and the early postnatal period.The Cochrane database of systematic reviews · 2021Pooled it
- Epidural therapy for the treatment of severe pre-eclampsia in non labouring women.The Cochrane database of systematic reviews · 2017Pooled it
- Aspirin and/or heparin for women with unexplained recurrent miscarriage with or without inherited thrombophilia.The Cochrane database of systematic reviews · 2014Pooled it
- Antithrombotic therapy for improving maternal or infant health outcomes in women considered at risk of placental dysfunction.The Cochrane database of systematic reviews · 2013Pooled it
- Prophylaxis for venous thromboembolic disease in pregnancy and the early postnatal period.The Cochrane database of systematic reviews · 2010Pooled it
- A systematic review of Cochrane anticoagulation reviews.Medscape journal of medicine · 2009Pooled it
- A review of the methodological features of systematic reviews in maternal medicine.BMC medicine · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThrombophilias, which are associated with a predisposition to thrombotic events, have been implicated in adverse obstetrical outcomes such as intrauterine growth restriction, stillbirth, severe early onset pre-eclampsia, and placental abruption. Heparin administration in pregnancy may reduce the risk of these events.
objectivesThe objective of this review was to assess the effects of heparin on pregnancy outcomes for women with a thrombophilia. SEARCH STRATEGY: We searched the Cochrane Pregnancy and Childbirth Group trials register (July 2002), MEDLINE, EMBASE, CINAHL, Scidex (via OVID Technologies - July 2002) and reference lists and personal files. SELECTION CRITERIA: Randomized controlled trials comparing heparin with placebo or no treatment, or randomized controlled trials comparing any two treatments. Quasi randomized studies would be included. DATA COLLECTION AND ANALYSIS: Data would be abstracted from identified studies and recorded on a paper form by two reviewers. MAIN
resultsNo studies were included. REVIEWER'S
conclusionsThere are no completed trials to determine the effects of heparin on pregnancy outcomes for women with a thrombophilia.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.