SynthesisSurgical endoscopy2003
Abdominal symptoms: do they disappear after cholecystectomy?
Synthesis in Surgical endoscopy, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Persistent and de novo symptoms after cholecystectomy: a systematic review of cholecystectomy effectiveness.Surgical endoscopy · 2013Pooled it
- Effects of Rowachol on prevention of postcholecystectomy pain after laparoscopic cholecystectomy: prospective multicenter randomized controlled trial.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2016Trial
- Trial
- Septated gallbladder: a rare congenital anomaly and its clinical implications.Journal of surgical case reports · 2026Article
- Demography, Spectrum, and Characteristics of Symptoms Associated With Post-operative Relief After Cholecystectomy.Cureus · 2023Article
- Development of functional gastrointestinal disorder symptoms following laparoscopic cholecystectomy: a prospective cohort study.Frontiers in medicine · 2023Article
- Long-term patient-reported outcomes following laparoscopic cholecystectomy: A prospective multicenter observational study.Medicine · 2020Observational
- Etiologies of Long-Term Postcholecystectomy Symptoms: A Systematic Review.Gastroenterology research and practice · 2019Review
- Postcholecystectomy syndrome: symptom clusters after laparoscopic cholecystectomy.Annals of surgical treatment and research · 2018Article
- Which Abdominal Symptoms are Associated with Clinical Events in a Population Unaware of Their Gallstones? a Cohort Study.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2017Article
- Consistency of patient-reported outcomes after cholecystectomy and their implications on current surgical practice: a prospective multicenter cohort study.Surgical endoscopy · 2017Article
- Elective laparoscopic cholecystectomy for symptomatic uncomplicated gallstone disease: do the symptoms disappear?Surgical endoscopy · 2014Article
- Fate of dyspeptic or colonic symptoms after laparoscopic cholecystectomy.Journal of neurogastroenterology and motility · 2014Article
- EPISOD puts an end to sphincter of Oddi dysfunction type III.Annals of gastroenterology · 2014Article
- Symptoms resolution post-cholecystectomy: patient selection is very important.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2012Article
- Post-cholecystectomy symptoms were caused by persistence of a functional gastrointestinal disorder.World journal of gastroenterology · 2012Article
- Preoperative symptoms of irritable bowel syndrome predict poor outcome after laparoscopic cholecystectomy.Surgical endoscopy · 2011Article
- Trait anxiety predicts outcome 6 weeks after cholecystectomy. A prospective follow-up study.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2011Article
- Prospective 6 weeks follow-up post-cholecystectomy: the predictive value of pre-operative symptoms.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2009Article
- Pain persists in many patients five years after removal of the gallbladder: observations from two randomized controlled trials of symptomatic, noncomplicated gallstone disease and acute cholecystitis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary TractArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the effect of cholecystectomy in patients with gallstones on preoperative abdominal symptoms.
methodsA systematic search was made of the Medline database in combination with reference checking. Articles were excluded if patients aged <18 years, symptom relief rates could not be calculated, if follow-up after cholecystectomy was less than 1 month, or when the included patients were at extraordinary risk for a complicated outcome. Potential differences in relief rates due to patient selection, retrospective versus prospective design, duration of follow-up, or intervention were analyzed using logistic regression.
resultsThe pooled relief rate for "biliary pain" was high 92% (95% confidence interval 86 to 96%). Symptom relief rates were consistently higher in studies that included acute cholecystectomies. For upper abdominal pain--without restrictions for intensity or duration--pooled relief rates ranged from 72% (66 to 77%) after elective cholecystectomy, to 86% (83 to 91%) after acute cholecystectomy. The relief rate of food intolerance was higher in studies with a follow-up < or =12 months (88%, 76 to 91%) compared to studies with a follow-up of more than 12 months (65%, 55 to 74%).
conclusionIn almost all patients with gallstones biliary pain disappeared after cholecystectomy. There is insufficient evidence, however, that this relief was due to cholecystectomy. Relief rates of other isolated symptoms were low in patients with an elective cholecystectomy. A proper evaluation of the effectiveness of cholecystectomy in terms of abdominal symptom relief rates requires a randomized trial.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.