ReviewVirchows Archiv : an international journal of pathology2003
Amyloid in surgical pathology.
Review in Virchows Archiv : an international journal of pathology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
26 citing papers in PubMed.
- Age-related TFEB downregulation in proximal tubules causes systemic metabolic disorders and occasional apolipoprotein A4-related amyloidosis.JCI insight · 2024Article
- Cutaneous Involvement in Diseases with Plasma Cell Differentiation: Diagnostic Approach.Current oncology (Toronto, Ont.) · 2022Article
- Renal amyloidosis: a new time for a complete diagnosis.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022Review
- Antibody-Mediated Rejection and Recurrent Primary Disease: Two Main Obstacles in Abdominal Kidney, Liver, and Pancreas Transplants.Journal of clinical medicine · 2021Review
- Amyloid light-chain amyloidosis with haemorrhagic bullous eruption disclosing multiple myeloma.International wound journal · 2020Article
- A case report of pulmonary amyloidosis recognized by detection of AA amyloid exclusively in alveolar macrophages.Respiratory medicine case reports · 2020Article
- Origins of a pervasive, erroneous idea: The "green birefringence" of Congo red-stained amyloid.International journal of experimental pathology · 2019Review
- Local vs. systemic pulmonary amyloidosis-impact on diagnostics and clinical management.Virchows Archiv : an international journal of pathology · 2018Article
- Diagnosis and management of transthyretin familial amyloid polyneuropathy in Japan: red-flag symptom clusters and treatment algorithm.Orphanet journal of rare diseases · 2018Review
- A rare case of primary thyroid amyloidosis.International journal of surgery case reports · 2018Article
- Bilateral multifocal lower extremity localized soft tissue amyloidomas: case report with ultrasonographic characterization.Skeletal radiology · 2017Article
- Cardiac Amyloidosis, An Infiltrative Heart Disease Presenting as Arrhythmia-A Case Report.Journal of clinical and diagnostic research : JCDR · 2017Article
- First European consensus for diagnosis, management, and treatment of transthyretin familial amyloid polyneuropathy.Current opinion in neurology · 2016Review
- Renal AA Amyloidosis in Patients with Type 2 Diabetes Mellitus.Nephron extra · 2014Article
- Recent advances in transthyretin amyloidosis therapy.Translational neurodegeneration · 2014Review
- Pulmonary manifestations of Sjögren's syndrome.Current allergy and asthma reports · 2013Review
- Nodular goiter with amyloid deposition in an elderly patient: fine-needle cytology diagnosis and review of the literature.BMC surgery · 2013Review
- Amyloid deposition in rheumatoid arthritis of the hip.Rheumatology international · 2012Article
- AL-Amyloidosis Presenting with Negative Congo Red Staining in the Setting of High Clinical Suspicion: A Case Report.Case reports in nephrology · 2012Article
- Strong transthyretin immunostaining: potential pitfall in cardiac amyloid typing.The American journal of surgical pathology · 2011Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Amyloid is defined as a proteinaceous tissue deposit that shows a typical green birefringence in polarized light after staining with Congo red, the presence of non-branching linear fibrils of indefinite length with a mean diameter of 10 nm, and a distinct X-ray diffraction pattern consistent with Pauling's model of a cross beta-fibril. Amyloid may deposit locally or may present as a systemic disease. The origin of amyloid is diverse: 25 different fibril proteins have been described so far. The precursor proteins differ from each other in their primary structures and functions. The only common denominator is the propensity to form anti-parallel cross beta-fibrils under certain circumstances. Early diagnosis of amyloid is still a major challenge in surgical pathology. Histological proof can be obtained using Congo-red staining and polarization microscopy. However, small deposits may be difficult to discern, and sensitivity can be improved using fluorescence microscopy. Classification of amyloid is mandatory, since amyloid is treatable and different treatment regimens are applied to different amyloid diseases. This review focuses on the epidemiology, clinical features, pathology and diagnosis of amyloid in surgical pathology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.