Evidence map›Paper›PMID 12800502›Full record

ArticleFolia microbiologica2003

Trehalose, glycogen and ethanol metabolism in the gcr1 mutant of Saccharomyces cerevisiae.

T Seker, H Hamamci

Abstract read
PubMed Publisher
In one paragraph

Article in Folia microbiologica, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

T SekerDepartment of Biotechnology, Middle East Technical University, 06 531 Ankara, Turkey. tseker@biocentrum.dtu.dk
H Hamamci

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since Gcr1p is pivotal in controlling the transcription of glycolytic enzymes and trehalose metabolism seems to be one of the control points of glycolysis, we examined trehalose and glycogen synthesis in response to 2% glucose pulse during batch growth in gcr1 (glucose regulation-1) mutant lacking fully functional glycolytic pathway and in the wild-type strain. An increase in both trehalose and glycogen stores was observed 1 and 2 h after the pulse followed by a steady decrease in both the wild-type and the gcr1 mutant. The accumulation was faster while the following degradation was slower in gcr1 cells compared to wild-type ones. Although there was no distinct glucose consumption in the mutant cells it seemed that the glucose repression mechanism is similar in gcr1 mutant and in wild-type strain at least with respect to trehalose and glycogen metabolism.

Indexed as

MutationCulture MediaDNA-Binding ProteinsEthanolFungal ProteinsGene Expression Regulation, FungalGlycogenSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTranscription FactorsTrehaloseCulture MediaDNA-Binding ProteinsEthanolFungal ProteinsGCR1 protein, S cerevisiaeGlycogenSaccharomyces cerevisiae ProteinsTranscription FactorsTrehalose

Identifiers

PMID12800502

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.