Evidence map›Paper›PMID 12791924›Full record

ArticleJournal of clinical microbiology2003

Plasma versus serum for detection of herpes simplex virus type 2-specific immunoglobulin G antibodies with a glycoprotein G2-based enzyme immunoassay.

Thomas L Cherpes, Leslie A Meyn, Sharon L Hillier

Open access · greenAbstract readComparative Study
In one paragraph

Article in Journal of clinical microbiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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  10. The diagnosis of genital herpes - beyond culture: An evidence-based guide for the utilization of polymerase chain reaction and herpes simplex virus type-specific serology.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2007
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Thomas L CherpesDepartment of Medicine, Division of Infectious Disease, Magee-Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.
Leslie A Meyn
Sharon L Hillier
Magee-Womens Research Institute · US

Funding

HPTN CENTRAL LABORATORYU01AI046745 · NIAID · JOHNS HOPKINS UNIVERSITY · PI JACKSON, JAY B · 2000 to 2005
$20.8M
STDS AND THE PATHOGENESIS OF SUBCLINICAL PIDR01AI041624 · NIAID · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI WIESENFELD, HAROLD C · 1998 to 2007
$3.5M
TRAINING IN AIDS &MOLECULAR MICROBIOLOGY/EPIDEMIOLOGYT32AI007333 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MELLORS, JOHN W · 1988 to 2009
$1.3M
NIAID NIH HHS R01 AI041624NIAID NIH HHS R01-AI-41624NIAID NIH HHS T32 AI007333NIAID NIH HHS T32-AI07333NIAID NIH HHS U01 AI046745NIAID NIH HHS U01-AI-46745
6 · The paper itself

Abstract

To evaluate the consonance between plasma and serum for the detection of herpes simplex virus type 2-specific immunoglobulin G antibodies, we compared results from concurrently obtained plasma and sera in 710 sexually active women by using a glycoprotein G2-based enzyme-linked immunosorbent assay (Focus Technologies, Cypress, Calif.) and found 98.9% agreement between the two specimen types. Plasma appears to be an acceptable matrix for use with this assay.

Indexed as

Antibody SpecificityAntibodies, ViralEnzyme-Linked Immunosorbent AssayFemaleHerpes GenitalisHerpesvirus 2, HumanHumansImmunoglobulin GSpecimen HandlingViral Envelope ProteinsAntibodies, ViralImmunoglobulin GViral Envelope Proteins

Identifiers

PMID12791924
PMCPMC156559
OpenAlexW2125015526

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.