Evidence map›Paper›PMID 12791899›Full record

ArticleJournal of clinical microbiology2003

Comparison of results obtained by testing with three different agar media and by the NCCLS M27-A method for in vitro testing of fluconazole against Candida spp.

M Carmen Rubio, Joaquina Gil, Inmaculada Ramírez De Ocáriz, Rafael Benito, Antonio Rezusta

Open access · greenAbstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Antifungal activity of Piper diospyrifolium Kunth (Piperaceae) essential oil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2011
    Article
  5. Article
  6. Antifungal activity of the essential oil from Calendula officinalis L. (asteraceae) growing in Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2008
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

M Carmen RubioMicrobiology, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain. mcrubio@posta.unizar.es
Joaquina Gil
Inmaculada Ramírez De Ocáriz
Rafael Benito
Antonio Rezusta
Hospital Clínico Universitario Lozano Blesa · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluconazole susceptibilities of 150 Candida isolates were determined by a 25- micro g fluconazole disk diffusion agar test and compared with the microdilution NCCLS M27-A method. The agar test used three different media and was read at 24 and 48 h. When only the susceptible and nonsusceptible categories were used, disk diffusion with Müeller-Hinton agar supplemented with 2% glucose and 0.5 micro g of methylene blue (MHGM) per ml had a 95.37% correlation with the MIC method at 24 h, followed by RPMI 1640-2% of glucose agar (correlation, 94%) and Shadomy medium (SHDM) (correlation, 92.6%). The growth of microcolonies inside the inhibition zones was common (>63%) in the RPMI and SHDM media and minimal with MHGM (8.7%). At 48 h, MHGM and SHDM still had a >91% correlation with the MIC, while RPMI results had dropped to 75%. The best overall agreement was obtained with C. dubliniensis (100%).

Indexed as

AgarAntifungal AgentsCandidaCulture MediaFluconazoleHumansMicrobial Sensitivity TestsAgarAntifungal AgentsCulture MediaFluconazole

Identifiers

PMID12791899
PMCPMC156545
OpenAlexW2091297178

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.