ArticleJournal of clinical microbiology2003
Direct isolation of Candida spp. from blood cultures on the chromogenic medium CHROMagar Candida.
Article in Journal of clinical microbiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Detection of Candida albicans by a sandwich assay using boronate affinity microspheres coupled with amphotericin B-time-resolved fluorescent microspheres.Analytical and bioanalytical chemistry · 2026Article
- Diagnostic Biomarkers for Invasive Candidiasis: A Clinician-Oriented Review.Journal of fungi (Basel, Switzerland) · 2026Review
- Epidemiological Characteristics and Mortality Predictors of Candidemia Due toJournal of fungi (Basel, Switzerland) · 2025Article
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- Production of herbal toothpaste: Physical, organoleptic, phyto-compound, and antimicrobial properties.Heliyon · 2023Article
- What IsMicroorganisms · 2022Review
- The Changing Landscape of Invasive Fungal Infections in ICUs: A Need for Risk Stratification to Better Target Antifungal Drugs and the Threat of Resistance.Journal of fungi (Basel, Switzerland) · 2022Review
- Continuing Shifts in Epidemiology and Antifungal Susceptibility Highlight the Need for Improved Disease Management of Invasive Candidiasis.Microorganisms · 2022Review
- Medically important Candida spp. identification: an era beyond traditional methods.Turkish journal of medical sciences · 2022Article
- Raman Spectroscopy of OralInternational journal of molecular sciences · 2022Article
- Performance of Two Novel Chromogenic Media for the Identification of Multidrug-Resistant Candida auris Compared with Other Commercially Available Formulations.Journal of clinical microbiology · 2021Article
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- Vacuolar Sequestration of Azoles, a Novel Strategy of Azole Antifungal Resistance Conserved across Pathogenic and Nonpathogenic Yeast.Antimicrobial agents and chemotherapy · 2019Article
- Isolation and Speciation ofJournal of clinical and diagnostic research : JCDR · 2017Article
- Advances in Candida detection platforms for clinical and point-of-care applications.Critical reviews in biotechnology · 2017Review
- Performance of chromogenic media for Candida in rapid presumptive identification of Candida species from clinical materials.Pharmacognosy research · 2015Article
- MicroRNA Expression Profiling of Human Respiratory Epithelium Affected by Invasive Candida Infection.PloS one · 2015Article
- Candiduria: prevalence and trends in antifungal susceptibility in a tertiary care hospital of mangalore.Journal of clinical and diagnostic research : JCDR · 2013Article
- Accuracy of species-level identification of yeast isolates from blood cultures from 10 university hospitals in South Korea by use of the matrix-assisted laser desorption ionization-time of flight mass spectrometry-based Vitek MS system.Journal of clinical microbiology · 2013Article
- First case report of bloodstream infection due to a Candida species closely related to the novel species Candida pseudorugosa.Journal of clinical microbiology · 2012Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CHROMagar Candida is a selective and differential chromogenic medium that has been shown to be useful for identification of Candida albicans, Candida krusei, Candida tropicalis, and perhaps Candida glabrata. Colony morphology and color have been well defined when CHROMagar Candida has been used to isolate yeast directly from clinical specimens, including stool, urine, respiratory, vaginal, oropharyngeal, and esophageal sources. Direct isolation of yeast on CHROMagar Candida from blood cultures has not been evaluated. We evaluated whether the color and colony characteristics produced by Candida spp. on CHROMagar Candida were altered when yeasts were isolated directly from blood cultures. Fifty clinical isolates of Candida were inoculated into aerobic and anaerobic blood culture bottles and incubated at 35 degrees C in an automated blood culture system. When growth was detected, an aliquot was removed and plated onto CHROMagar Candida. As a control, CHROMagar Candida plates were inoculated with the same isolate of yeast grown on Sabouraud dextrose agar simultaneously. No significant difference was detected in color or colony morphology between the blood and control isolates in any of the tested organisms. All C. albicans (n = 12), C. tropicalis (n = 12), C. glabrata (n = 9), and C. krusei (n = 5) isolates exhibited the expected species-specific colony characteristics and color, whether isolated directly from blood or from control cultures. CHROMagar Candida can be reliably used for direct isolation of yeast from blood cultures. Direct isolation could allow mycology laboratories to more rapidly identify Candida spp., enable clinicians to more quickly make antifungal agent selections, and potentially decrease patient morbidity and mortality.
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