Evidence map›Paper›PMID 12791853›Full record

ArticleJournal of clinical microbiology2003

Survey of emm gene sequences from pharyngeal Streptococcus pyogenes isolates collected in Spain and their relationship with erythromycin susceptibility.

Sebastián Albertí, César García-Rey, María A Domínguez, Lorenzo Aguilar, Emilia Cercenado, Miguel Gobernado, Adela García-Perea, Spanish Surviellance Group for Respiratory Pathogens

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
6.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 52 citations in OpenAlex.

  1. Molecular epidemiology and genomics of group A Streptococcus.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2015
    Review
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  8. Population biology of the human restricted pathogen, Streptococcus pyogenes.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2009
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Sebastián AlbertíUnidad de Investigación, Hospital Universitario Son Dureta, Palma de Mallorca, Spain. salberti@hsd.es
César García-Rey
María A Domínguez
Lorenzo Aguilar
Emilia Cercenado
Miguel Gobernado
Adela García-Perea
Spanish Surviellance Group for Respiratory Pathogens
GlaxoSmithKline (India) · INBellvitge University Hospital · ESHospital General Universitario Gregorio Marañón · ESHospital Universitari i Politècnic La Fe · ESHospital Universitario La Paz · ESHospital Universitario Son Dureta · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted a nationwide survey of the variable 5' emm (M protein gene) sequences from 614 pharyngeal Streptococcus pyogenes isolates susceptible (299 isolates) and resistant (315 isolates) to erythromycin that were isolated in Spain from 1996 to 1999. Almost 98% of these isolates had emm sequences in agreement with previously recorded M antigen association. We only identified a new 5' emm sequence in 17 isolates. Nine different emm types accounted for 85% of the S. pyogenes isolates susceptible to erythromycin. By contrast, only 3 emm types accounted for 70% of the erythromycin-resistant isolates. Further characterization of these isolates by ribotyping and pulsed-field gel electrophoresis indicated that high frequency of erythromycin resistance in Spain is due to few clones.

Indexed as

Antigens, BacterialAnti-Bacterial AgentsBacterial Outer Membrane ProteinsCarrier ProteinsDrug Resistance, BacterialElectrophoresis, Gel, Pulsed-FieldErythromycinHumansMicrobial Sensitivity TestsMolecular Sequence DataPharyngitisPharynxRibotypingSpainStreptococcal InfectionsStreptococcus pyogenesAnti-Bacterial AgentsAntigens, BacterialBacterial Outer Membrane ProteinsCarrier ProteinsErythromycinstreptococcal M protein

Identifiers

PMID12791853
PMCPMC156550
OpenAlexW2130081299

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.