ArticleJournal of clinical microbiology2003
Molecular characterization of ampicillin-resistant Enterococcus faecium isolates from hospitalized patients in Norway.
Article in Journal of clinical microbiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 50 citations in OpenAlex.
- Multidrug-resistant Enterococcus faecium strains enter the Norwegian marine environment through treated sewage.MicrobiologyOpen · 2024Article
- Antimicrobial Resistance, Biofilm Formation, and Virulence Genes inAntibiotics (Basel, Switzerland) · 2022Article
- Rapid Detection ofBioMed research international · 2022Article
- Molecular identification and antibiotic resistance of bacteriocinogenic lactic acid bacteria isolated from table olives.Archives of microbiology · 2021Article
- Antibiotic Susceptibility Patterns, Biofilm Formation andInternational journal of environmental research and public health · 2019Article
- Antimicrobial Resistance inMicrobiology spectrum · 2018Review
- High genetic diversity of Enterococcus faecium and Enterococcus faecalis clinical isolates by pulsed-field gel electrophoresis and multilocus sequence typing from a hospital in Malaysia.BioMed research international · 2013Article
- Characterization of hospital-associated lineages of ampicillin-resistant Enterococcus faecium from clinical cases in dogs and humans.Frontiers in microbiology · 2013Article
- High-throughput sequencing reveals the incomplete, short-term recovery of infant gut microbiota following parenteral antibiotic treatment with ampicillin and gentamicin.Antimicrobial agents and chemotherapy · 2012Article
- Emergence of clonal complex 17 Enterococcus faecium in The Netherlands.Journal of clinical microbiology · 2008Article
- High-level ciprofloxacin resistance from point mutations in gyrA and parC confined to global hospital-adapted clonal lineage CC17 of Enterococcus faecium.Journal of clinical microbiology · 2006Article
- Prevalence, persistence, and molecular characterization of glycopeptide-resistant enterococci in Norwegian poultry and poultry farmers 3 to 8 years after the ban on avoparcin.Applied and environmental microbiology · 2006Article
- Population structure of Enterococcus faecium causing bacteremia in a Spanish university hospital: setting the scene for a future increase in vancomycin resistance?Antimicrobial agents and chemotherapy · 2005Article
- Global spread of vancomycin-resistant Enterococcus faecium from distinct nosocomial genetic complex.Emerging infectious diseases · 2005Article
- Persistence of animal and human glycopeptide-resistant enterococci on two Norwegian poultry farms formerly exposed to avoparcin is associated with a widespread plasmid-mediated vanA element within a polyclonal enterococcus faecium population.Applied and environmental microbiology · 2005Article
- Multiple-locus variable-number tandem repeat analysis, a novel typing scheme to study the genetic relatedness and epidemiology of Enterococcus faecium isolates.Journal of clinical microbiology · 2004Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The genetic relationship of 81 ampicillin-resistant and 21 ampicillin-susceptible Enterococcus faecium isolates from clinical infections and rectal screening in hospitalized patients in Norway was studied by pulsed-field gel electrophoresis (PFGE) and amplified fragment length polymorphism (AFLP). PFGE showed 55 different banding patterns, and 65 of the isolates could be grouped into one large group. With AFLP, 46 patterns were discerned, and 74 isolates clustered in one group. In general, the isolates had a higher degree of similarity than with PFGE. The purK gene, which is one of the targets of the E. faecium multilocus sequence typing scheme, was sequenced. Eleven different purK alleles could be discerned, with the majority of isolates (n = 80) harboring allele 1. With only two exceptions, all strains carrying purK-1 clustered in the same PFGE and AFLP groups, indicating a good correlation between PFGE type, AFLP type, and purK allele. Genetic polymorphism of a 571-bp PCR fragment of the C-terminal domain of the penicillin-binding protein 5 gene (pbp5) was determined, and sequence differences were associated with the level of ampicillin resistance. This study indicates that the majority of ampicillin-resistant E. faecium strains in Norway belong to a distinct genetic lineage of closely related genotypes. Rectal and clinical isolates were generally indistinguishable, and differences in clonal distribution and allele polymorphism were found mainly between ampicillin-resistant and -susceptible isolates.
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