SynthesisBMJ (Clinical research ed.)2003
Meta-analysis of data on costs from trials of counselling in primary care: using individual patient data to overcome sample size limitations in economic analyses.
Synthesis in BMJ (Clinical research ed.), 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled it
- Counselling for mental health and psychosocial problems in primary care.The Cochrane database of systematic reviews · 2011Pooled it
- On-site mental health workers delivering psychological therapy and psychosocial interventions to patients in primary care: effects on the professional practice of primary care providers.The Cochrane database of systematic reviews · 2009Pooled it
- Economic evaluation alongside a single RCT of an integrative psychotherapeutic nursing home programme.BMC health services research · 2013Trial
- Annual research review: Child and adolescent mental health interventions: a review of progress in economic studies across different disorders.Journal of child psychology and psychiatry, and allied disciplines · 2014Review
- Therapeutic identification of depression in young people: lessons from the introduction of a new technique in general practice.The British journal of general practice : the journal of the Royal College of General Practitioners · 2012Article
- The statistical pitfalls of the partially randomized preference design in non-blinded trials of psychological interventions.International journal of methods in psychiatric research · 2011Article
- Using and interpreting cost-effectiveness acceptability curves: an example using data from a trial of management strategies for atrial fibrillation.BMC health services research · 2006Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the feasibility of overcoming sample size limitations in economic analyses of clinical trials through meta-analysis of data on individual patients from multiple trials.
designMeta-analysis of individual patient data from trials of counselling in primary care compared with usual care by a general practitioner.
settingPrimary care. PATIENTS: People with mental health problems.
main outcome measuresDirect treatment costs, depressive symptoms, and cost effectiveness.
resultsMeta-analysis of individual patient data proved feasible. The results showed that the previous analyses of individual trials were underpowered to provide useful conclusions about the cost comparisons. The results are sensitive to assumptions made about the costs of sessions with a counsellor and the management of patients by a general practitioner.
conclusionsMeta-analysis of individual patient data may assist in overcoming sample size limitations in economic analyses. Although feasible, such analysis has shortcomings that may limit the validity of the results. The relative costs and benefits of this method, as opposed to further collection of primary data, are as yet unclear.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.