ArticleProceedings of the National Academy of Sciences of the United States of America2003
Germ-line transgenesis of the Tc1/mariner superfamily transposon Minos in Ciona intestinalis.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Protocol for reconstructing 2D and 3D peptide atlases of the Ciona cerebral ganglion at single-cell resolution.STAR protocols · 2026Article
- The tunicate Ciona.Nature methods · 2025Article
- Two- and three-dimensional neuropeptidomic landscape in the central nervous system of an invertebrate chordate,iScience · 2025Article
- A simple inland culture system provides insights into ascidian post-embryonic developmental physiology.Open biology · 2025Article
- Stable germline transgenesis using the Minos Tc1/mariner element in the sea urchin Lytechinus pictus.Development (Cambridge, England) · 2024Article
- Minos and Restless transposon insertion mutagenesis of psychrotrophic fungus for red pigment synthesis adaptive to normal temperature.Bioresources and bioprocessing · 2022Article
- Contemporary Transposon Tools: A Review and Guide through Mechanisms and Applications ofInternational journal of molecular sciences · 2021Review
- Vasopressin Promoter Transgenic and Vasopressin Gene-Edited Ascidian,Frontiers in endocrinology · 2021Article
- The ventral peptidergic system of the adult ascidian Ciona robusta (Ciona intestinalis Type A) insights from a transgenic animal model.Scientific reports · 2020Article
- Single-cell transcriptome profiling of the Ciona larval brain.Developmental biology · 2019Article
- piRNA-like small RNAs are responsible for the maternal-specific knockdown in the ascidian Ciona intestinalis Type A.Scientific reports · 2018Article
- The nervous system of the adult ascidian Ciona intestinalis Type A (Ciona robusta): Insights from transgenic animal models.PloS one · 2017Article
- Transcriptional regulation of a horizontally transferred gene from bacterium to chordate.Proceedings. Biological sciences · 2016Article
- CRISPR/Cas9-mediated gene knockout in the ascidian Ciona intestinalis.Development, growth & differentiation · 2014Article
- Transposon-mediated targeted and specific knockdown of maternally expressed transcripts in the ascidian Ciona intestinalis.Scientific reports · 2014Article
- Article
- Functional genetics for all: engineered nucleases, CRISPR and the gene editing revolution.EvoDevo · 2014Review
- Review
- Genomic integration and germline transmission of plasmid injected into crustacean Daphnia magna eggs.PloS one · 2012Article
- Ependymal cells of chordate larvae are stem-like cells that form the adult nervous system.Nature · 2011Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The tadpole larva of the basal chordate Ciona intestinalis has the most simplified, basic body-plan of chordates. Because it has a compact genome with a complete draft sequence, a large quantity of EST/cDNA information, and a short generation time, Ciona is a suitable model for future genetics. We establish here a transgenic technique in Ciona that uses the Tc1/mariner superfamily transposon Minos. Minos was integrated efficiently into the genome of germ cells and transmitted stably to subsequent generations. In addition, an enhancer-trap line was obtained. This is a demonstration of efficient, Minos-mediated transgenesis in marine invertebrates.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.