ArticleApplied and environmental microbiology2003
Population genetics of Vibrio vulnificus: identification of two divisions and a distinct eel-pathogenic clone.
Article in Applied and environmental microbiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 47 citations in OpenAlex.
- Harnessing the intragenomic variability of rRNA operons to improve differentiation of Vibrio species.Scientific reports · 2024Article
- Identification of potential pathogenic targets and survival strategies ofFrontiers in cellular and infection microbiology · 2023Article
- Isolation, detection of virulence genes, antibiotic resistance genes, plasmid profile, and molecular typing amongVeterinary world · 2019Article
- Role of anaerobiosis in capsule production and biofilm formation in Vibrio vulnificus.Infection and immunity · 2015Article
- Article
- Genome-wide SNP-genotyping array to study the evolution of the human pathogen Vibrio vulnificus biotype 3.PloS one · 2014Article
- Comparative genomic analysis of clinical and environmental Vibrio vulnificus isolates revealed biotype 3 evolutionary relationships.Frontiers in microbiology · 2014Article
- Pyrosequencing-based comparative genome analysis of Vibrio vulnificus environmental isolates.PloS one · 2012Article
- Polyphyletic origin of Vibrio vulnificus biotype 2 as revealed by sequence-based analysis.Applied and environmental microbiology · 2011Article
- Genetic characterization of Vibrio vulnificus strains from tilapia aquaculture in Bangladesh.Applied and environmental microbiology · 2010Article
- Clinical characteristics and molecular subtyping of Vibrio vulnificus illnesses, Israel.Emerging infectious diseases · 2008Article
- Population structures of two genotypes of Vibrio vulnificus in oysters (Crassostrea virginica) and seawater.Applied and environmental microbiology · 2008Article
- Comparison of direct genome restriction enzyme analysis and pulsed-field gel electrophoresis for typing of Vibrio vulnificus and their correspondence with multilocus sequence typing data.Applied and environmental microbiology · 2007Article
- Vibrio vulnificus typing based on simple sequence repeats: insights into the biotype 3 group.Journal of clinical microbiology · 2007Article
- Emergence of a virulent clade of Vibrio vulnificus and correlation with the presence of a 33-kilobase genomic island.Applied and environmental microbiology · 2007Article
- Refined medium for direct isolation of Vibrio vulnificus from oyster tissue and seawater.Applied and environmental microbiology · 2007Article
- Genetic distinctions among clinical and environmental strains of Vibrio vulnificus.Applied and environmental microbiology · 2006Article
- Hybrid Vibrio vulnificus.Emerging infectious diseases · 2005Article
- Protocol for specific isolation of virulent strains of Vibrio vulnificus serovar E (biotype 2) from environmental samples.Applied and environmental microbiology · 2004Article
- Sepsis with bullous necrotizing skin lesions due to vibrio vulnificus acquired through recreational activities in the Baltic Sea.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2004Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic relationships among 62 Vibrio vulnificus strains of different geographical and host origins were analyzed by multilocus enzyme electrophoresis (MLEE), random amplification of polymorphic DNA (RAPD), and sequence analyses of the recA and glnA genes. Out of 15 genetic loci analyzed by MLEE, 11 were polymorphic. Cluster analysis identified 43 distinct electrophoretic types (ETs) separating the V. vulnificus population into two divisions (divisions I and II). One ET (ET 35) included all indole-negative isolates from diseased eels worldwide (biotype 2). A second ET (ET 2) marked all of the strains from Israel isolated from patients who handled St. Peter's fish (biotype 3). RAPD analysis of the 62 V. vulnificus isolates identified 26 different profiles separated into two divisions as well. In general, this subdivision was comparable (but not identical) to that observed by MLEE. Phylogenetic analysis of 543 bp of the recA gene and of 402 bp of the glnA gene also separated the V. vulnificus population into two major divisions in a manner similar to that by MLEE and RAPD. Sequence data again indicated the overall subdivision of the V. vulnificus population into different biotypes. In particular, indole-negative eel-pathogenic isolates (biotype 2) on one hand and the Israeli isolates (biotype 3) on the other tended to cluster together in both gene trees. None of the methods showed an association between distinct clones and human clinical manifestations. Furthermore, except for the Israeli strains, only minor clusters comprising geographically related isolates were observed. In conclusion, all three approaches (MLEE, RAPD, and DNA sequencing) generated comparable but not always equivalent results. The significance of the two divisions (divisions I and II) still remains to be clarified, and a reevaluation of the definition of the biotypes is also needed.
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