Exploiting the redundancy in the immune system: vaccines can mediate protection by eliciting 'unnatural' immunity.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

22 citing papers in PubMed.

1. Cryptococcal Meningitis Treatment Beyond HIV: Recognizing the Need for Individualized Immune-Based Strategies.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
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2. Progress towards the Elusive Mastitis Vaccines.Vaccines · 2022
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3. Excreted Trypanosoma brucei proteins inhibit Plasmodium hepatic infection.PLoS neglected tropical diseases · 2021
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4. Implications of Coronavirus Disease 2019 (COVID-19) Antibody Dynamics for Immunity and Convalescent Plasma Therapy.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
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5. Human gut mycobiota tune immunity via CARD9-dependent induction of anti-fungal IgG antibodies.Cell · 2021
   Article
6. Subdominance in Antibody Responses: Implications for Vaccine Development.Microbiology and molecular biology reviews : MMBR · 2020
   Review
7. Update on Chlamydia trachomatis Vaccinology.Clinical and vaccine immunology : CVI · 2017
   Review
8. B-Cell-Deficient and CD8 T-Cell-Depleted Gnotobiotic Pigs for the Study of Human Rotavirus Vaccine-Induced Protective Immune Responses.Viral immunology · 2016
   Article
9. Alterations in immunodominance of Streptococcus mutans AgI/II: lessons learned from immunomodulatory antibodies.Vaccine · 2014
   Article
10. Hybrid phage displaying SLAQVKYTSASSI induces protection against Candida albicans challenge in BALB/c mice.Human vaccines & immunotherapeutics · 2014
    Article
11. Applying Convergent Immunity to Innovative Vaccines Targeting Staphylococcus aureus.Frontiers in immunology · 2014
    Review
12. Heat shock proteins enriched-promastigotes of Leishmania major inducing Th2 immune response in BALB/c mice.Iranian biomedical journal · 2012
    Article
13. A therapeutic anti-Streptococcus mutans monoclonal antibody used in human passive protection trials influences the adaptive immune response.Vaccine · 2011
    Article
14. A new murine model for testing vaccines against genital Chlamydia trachomatis infections in males.Vaccine · 2010
    Article
15. Protection of wild-type and severe combined immunodeficiency mice against an intranasal challenge by passive immunization with monoclonal antibodies to the Chlamydia trachomatis mouse pneumonitis major outer membrane protein.Infection and immunity · 2008
    Article
16. Advances in combating fungal diseases: vaccines on the threshold.Nature reviews. Microbiology · 2007
    Review
17. Essential role for humoral immunity during Ehrlichia infection in immunocompetent mice.Infection and immunity · 2005
    Article
18. Antibody-mediated immunomodulation: a strategy to improve host responses against microbial antigens.Infection and immunity · 2005
    Review
19. Surface proteins of Streptococcus agalactiae and related proteins in other bacterial pathogens.Clinical microbiology reviews · 2005
    Review
20. Modulation of polymorphonuclear cell interleukin-8 secretion by human monoclonal antibodies to type 8 pneumococcal capsular polysaccharide.Infection and immunity · 2003
    Article

Corrections and comments

• Comment on
  Vaccine immunity to pathogenic fungi overcomes the requirement for CD4 help in exogenous antigen presentation to CD8+ T cells: implications for vaccine development in immune-deficient hosts.2003

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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