Trial reportThorax2003
Clinical trial comparing nicotine replacement therapy (NRT) plus brief counselling, brief counselling alone, and minimal intervention on smoking cessation in hospital inpatients.
Trial report in Thorax, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 12 syntheses or guidelines pooled it, 122 citations in OpenAlex.
- Korean Clinical Practice Guideline of Korean Society for Research on Nicotine and Tobacco (KSRNT) and National Evidence-based Healthcare Collaborating Agency (NECA) on Treatment of Tobacco Use 2024.Journal of Korean medical science · 2025Guideline
- Interventions for smoking cessation in hospitalised patients.The Cochrane database of systematic reviews · 2024Pooled it
- Interventions for preventing weight gain after smoking cessation.The Cochrane database of systematic reviews · 2021Pooled it
- A Meta-Analysis of Transcranial Direct Current Stimulation on Substance and Food Craving: What Effect Do Modulators Have?Frontiers in psychiatry · 2020Pooled it
- Nicotine replacement therapy versus control for smoking cessation.The Cochrane database of systematic reviews · 2018Pooled it
- Individual behavioural counselling for smoking cessation.The Cochrane database of systematic reviews · 2017Pooled it
- Combined pharmacotherapy and behavioural interventions for smoking cessation.The Cochrane database of systematic reviews · 2016Pooled it
- Interventions for smoking cessation in hospitalised patients.The Cochrane database of systematic reviews · 2012Pooled it
- Does the use of ingredients added to tobacco increase cigarette addictiveness?: a detailed analysis.Inhalation toxicology · 2012Pooled it
- Do point prevalence and prolonged abstinence measures produce similar results in smoking cessation studies? A systematic review.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2010Pooled it
- Smoking cessation interventions for hospitalized smokers: a systematic review.Archives of internal medicine · 2008Pooled it
- Effectiveness of smoking cessation therapies: a systematic review and meta-analysis.BMC public health · 2006Pooled it
- Effectiveness of Nicotine Replacement Therapy and Behavioral Intervention in Tobacco Cessation-A Tertiary Hospital-Based Randomized Controlled Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Trial
- Systematic identification and treatment of smokers by hospital based cessation practitioners in a secondary care setting: cluster randomised controlled trial.BMJ (Clinical research ed.) · 2013Trial
- A randomized placebo-controlled trial of varenicline for smoking cessation allowing flexible quit dates.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2012Trial
- Comparison of two smoking cessation interventions for inpatients.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e TisilogiaTrial
- Texas tobacco quitline knowledge, attitudes, and practices within healthcare agencies serving individuals with behavioral health needs: A multimethod study.Preventive medicine reports · 2023Article
- "Cold turkey" or pharmacotherapy: Examination of tobacco cessation methods tried among smokers prior to developing head and neck cancer.Head & neck · 2019Article
- Efficacy of guided self-change for smoking cessation in chronic obstructive pulmonary disease patients: A randomized controlled clinical trial.Tobacco induced diseases · 2019Article
- Targeted Secure Messages to Facilitate Access to Tobacco Treatment Counseling for Veterans: Feasibility Study.JMIR mental health · 2018Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGuidelines recommend that smoking cessation interventions are offered in all clinical settings to all smokers willing to make a quit attempt. Since the effectiveness of routine provision of behavioural counselling and nicotine replacement therapy (NRT) to smokers admitted to hospital has not been established, a randomised controlled trial of these interventions given together compared with counselling alone or minimal intervention was performed in hospital inpatients.
methodsMedical and surgical inpatients who were current smokers at the time of admission were randomised to receive either usual care (no additional advice at admission), counselling alone (20 minute intervention with written materials), or NRT plus counselling (counselling intervention with a 6 week course of NRT). Continuous and point prevalence abstinence from smoking (validated by exhaled carbon monoxide <10 ppm) was measured at discharge from hospital and at 3 and 12 months, and self-reported reduction in cigarette consumption in smokers was assessed at 3 and 12 months.
results274 inpatient smokers were enrolled. Abstinence was higher in the NRT plus counselling group (n=91) than in the counselling alone (n=91) or usual care (n=92) groups. The difference between the groups was significant for validated point prevalence abstinence at discharge (55%, 43%, 37% respectively, p=0.045) and at 12 months (17%, 6%, 8%, p=0.03). The respective differences in continuous validated abstinence at 12 months were 11%, 4%, 8% (p=0.25). There was no significant difference between counselling alone and usual care, or in reduction in cigarette consumption between the treatment groups.
conclusionsNRT given with brief counselling to hospital inpatients is an effective routine smoking cessation intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.