ArticleNucleic acids research2003
Experimental and computational analysis of transcriptional start sites in the cyanobacterium Prochlorococcus MED4.
Article in Nucleic acids research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 47 citations in OpenAlex.
- Toward a genetic system in the marine cyanobacteriumAccess microbiology · 2020Article
- The primary transcriptome of the fast-growing cyanobacteriumBiotechnology for biofuels · 2018Article
- Comparative transcriptomics of two environmentally relevant cyanobacteria reveals unexpected transcriptome diversity.The ISME journal · 2014Article
- A microarray for assessing transcription from pelagic marine microbial taxa.The ISME journal · 2014Article
- Quantitative and functional characterization of the hyper-conserved protein of Prochlorococcus and marine Synechococcus.PloS one · 2014Article
- Sequence analysis of a complete 1.66 Mb Prochlorococcus marinus MED4 genome cloned in yeast.Nucleic acids research · 2012Article
- Unveiling Mycoplasma hyopneumoniae promoters: sequence definition and genomic distribution.DNA research : an international journal for rapid publication of reports on genes and genomes · 2012Article
- Transcriptome and proteome dynamics of a light-dark synchronized bacterial cell cycle.PloS one · 2012Article
- An experimentally anchored map of transcriptional start sites in the model cyanobacterium Synechocystis sp. PCC6803.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- A high resolution map of a cyanobacterial transcriptome.Genome biology · 2011Article
- Inactivation of alternative sigma factor 54 (RpoN) leads to increased acid resistance, and alters locus of enterocyte effacement (LEE) expression in Escherichia coli O157 : H7.Microbiology (Reading, England) · 2010Article
- Illumination stimulates cAMP receptor protein-dependent transcriptional activation from regulatory regions containing class I and class II promoter elements in Synechocystis sp. PCC 6803.Microbiology (Reading, England) · 2009Article
- Evidence for a major role of antisense RNAs in cyanobacterial gene regulation.Molecular systems biology · 2009Article
- Agr system of Listeria monocytogenes EGD-e: role in adherence and differential expression pattern.Applied and environmental microbiology · 2007Article
- Selection against spurious promoter motifs correlates with translational efficiency across bacteria.PloS one · 2007Article
- Translational control and target recognition by Escherichia coli small RNAs in vivo.Nucleic acids research · 2007Article
- The Rhizobium etli sigma70 (SigA) factor recognizes a lax consensus promoter.Nucleic acids research · 2006Article
- Identification of cyanobacterial non-coding RNAs by comparative genome analysis.Genome biology · 2005Article
- Multiple promoters are a common feature of mitochondrial genes in Arabidopsis.Nucleic acids research · 2005Article
- Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a nearly minimal oxyphototrophic genome.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In contrast to certain model eubacteria, little is known as to where transcription is initiated in the genomes of cyanobacteria, which are largely distinct from other prokaryotes. In this work, 25 transcription start sites (TSS) of 21 different genes of Prochlorococcus sp. MED4 were determined experimentally. The data suggest more than one TSS for the genes ftsZ, petH, psbD and ntcA. In contrast, the rbcL-rbcS operon encoding ribulose 1,5-bisphosphate carboxylase/oxygenase lacks a detectable promoter and is co-transcribed with the upstream located gene ccmK. The entire set of experimental data was used in a genome-wide scan for putative TSS in Prochlorococcus. A -10 element could be defined, whereas at the -35 position there was no element common to all investigated sequences. However, splitting the data set into sub-classes revealed different types of putative -35 boxes. Only one of them resembled the consensus sequence TTGACA recognized by the vegetative sigma factor (sigma70) of enterobacteria. Using a scoring matrix of the -10 element, more than 3000 TSS were predicted, about 40% of which were estimated to be functional. This is the first systematic study of transcription initiation sites in a cyanobacterium.
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