ArticleJournal of human genetics2003
Association study of autoimmune thyroid disease at 5q23-q33 in Japanese patients.
Article in Journal of human genetics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Polymorphisms in the ADRB2 gene and Graves disease: a case-control study and a meta-analysis of available evidence.BMC medical genetics · 2009Pooled it
- Linkage Analysis of the Chromosome 5q31-33 Region Identifies JAKMIP2 as a Risk Factor for Graves' Disease in the Chinese Han Population.Medical science monitor : international medical journal of experimental and clinical research · 2019Article
- Association between polymorphism within interleukin related genes and Graves' disease: a meta-analysis of 22 case-control studies.Oncotarget · 2017Article
- Thyrotropin Receptor Epitope and Human Leukocyte Antigen in Graves' Disease.Frontiers in endocrinology · 2016Review
- The -112G>A polymorphism of the secretoglobin 3A2 (SCGB3A2) gene encoding uteroglobin-related protein 1 (UGRP1) increases risk for the development of Graves' disease in subsets of patients with elevated levels of immunoglobulin E.Journal of applied genetics · 2011Article
- Polymorphisms in the interleukin 3 gene show strong association with susceptibility to Graves' disease in Chinese population.Genes and immunity · 2009Article
- beta-2-adrenergic receptor gene polymorphism confers susceptibility to Graves disease.International journal of molecular medicine · 2007Article
- Immunogenetics of Hashimoto's thyroiditis.Journal of autoimmune diseases · 2005Article
- Microsatellite genotyping of chromosome 14q13.2-14q13 in the vicinity of proteasomal gene PSMA6 and association with Graves' disease in the Latvian population.Immunogenetics · 2004Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As part of a genome scan to locate familial Graves' disease (GD) and Hashimoto's thyroiditis (HT) genes, an autoimmune thyroid disease (AITD) susceptibility locus has recently been identified at 5q31-q33 in a Japanese population. We performed an association study using six microsatellite markers located at this locus in a set of 440 unrelated Japanese AITD patients and 218 Japanese controls. We found significant allelic association between AITD and three markers located in 5q23-q33. GD demonstrated significant associations with two of these markers, while HT did not show significant associations with any markers. Further, when patients with GD were stratified according to clinical manifestations, the association was significantly different from the other subgroup of each category. These findings suggest the presence of susceptible genes of AITD, especially distinct subgroups of GD, in or near 5q23-q33.
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Registered trials
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