ArticleJournal of computational neuroscience
No parallel fiber volleys in the cerebellar cortex: evidence from cross-correlation analysis between Purkinje cells in a computer model and in recordings from anesthetized rats.
Article in Journal of computational neuroscience. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Purkinje cell models: past, present and future.Frontiers in computational neuroscience · 2024Review
- Coding Capacity of Purkinje Cells With Different Schemes of Morphological Reduction.Frontiers in computational neuroscience · 2019Article
- Robust transmission of rate coding in the inhibitory Purkinje cell to cerebellar nuclei pathway in awake mice.PLoS computational biology · 2017Article
- Article
- Stochastic Synchronization in Purkinje Cells with Feedforward Inhibition Could Be Studied with Equivalent Phase-Response Curves.Journal of mathematical neuroscience · 2015Article
- Ultra-rapid axon-axon ephaptic inhibition of cerebellar Purkinje cells by the pinceau.Nature neuroscience · 2014Article
- Article
- Synchrony and neural coding in cerebellar circuits.Frontiers in neural circuits · 2012Article
- The mysterious microcircuitry of the cerebellar nuclei.The Journal of physiology · 2011Review
- Determinants of synaptic integration and heterogeneity in rebound firing explored with data-driven models of deep cerebellar nucleus cells.Journal of computational neuroscience · 2011Article
- Neocortical networks entrain neuronal circuits in cerebellar cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009Article
- Cerebellar cortical molecular layer inhibition is organized in parasagittal zones.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2006Article
- Differential susceptibility to synaptic plasticity reveals a functional specialization of ascending axon and parallel fiber synapses to cerebellar Purkinje cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2006Article
- On the cerebello-cerebral interactions.Cerebellum (London, England) · 2006Article
- Differences in transmission properties and susceptibility to long-term depression reveal functional specialization of ascending axon and parallel fiber synapses to Purkinje cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2005Article
- Feed-forward inhibition shapes the spike output of cerebellar Purkinje cells.The Journal of physiology · 2005Article
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1 author at 1 institution in 1 country.
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Abstract
Purkinje cells aligned on the medio-lateral axis share a large proportion of their approximately 175,000 parallel fiber inputs. This arrangement has led to the hypothesis that movement timing is coded in the cerebellum by beams of synchronously active parallel fibers. In computer simulations I show that such synchronous activation leads to a narrow spike cross-correlation between pairs of Purkinje cells. This peak was completely absent when shared parallel fiber input was active in an asynchronous mode. To determine the presence of synchronous parallel fiber beams in vivo I recorded from pairs of Purkinje cells in crus IIa of anesthetized rats. I found a complete absence of precise spike synchronization, even when both cells were strongly modulated in their spike rate by trains of air-puff stimuli to the face. These results indicate that Purkinje cell spiking is not controlled by volleys of synchronous parallel fiber inputs in the conditions examined. Instead, the data support a model by which granule cells primarily control Purkinje cell spiking via dynamic population rate changes.
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