ArticleInfection and immunity2003
The FimH A27V mutation is pathoadaptive for urovirulence in Escherichia coli B2 phylogenetic group isolates.
Article in Infection and immunity, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Integrative Molecular and Structural Profiling of Escherichia coli Virulence Genes in Diabetes-Associated Infections.Current microbiology · 2026Article
- Pathogenicity assessment of Shiga toxin-producingFrontiers in microbiology · 2023Article
- The population genetics of pathogenic Escherichia coli.Nature reviews. Microbiology · 2021Review
- Characterization of mucosa-associated Escherichia coli strains isolated from Crohn's disease patients in Brazil.BMC microbiology · 2020Article
- Genetic and Phenotypic Features to Screen for Putative Adherent-InvasiveFrontiers in microbiology · 2019Article
- Conditional Function of Autoaggregative Protein Cah and CommonApplied and environmental microbiology · 2018Article
- Whole-genome comparison of urinary pathogenic Escherichia coli and faecal isolates of UTI patients and healthy controls.International journal of medical microbiology : IJMM · 2017Article
- Adaptation of Escherichia coli traversing from the faecal environment to the urinary tract.International journal of medical microbiology : IJMM · 2016Article
- The Adherent/Invasive Escherichia coli Strain LF82 Invades and Persists in Human Prostate Cell Line RWPE-1, Activating a Strong Inflammatory Response.Infection and immunity · 2016Article
- An Environmental Shiga Toxin-Producing Escherichia coli O145 Clonal Population Exhibits High-Level Phenotypic Variation That Includes Virulence Traits.Applied and environmental microbiology · 2016Article
- Metabolism and Fitness of Urinary Tract Pathogens.Microbiology spectrum · 2015Article
- Genomic characterisation of an endometrial pathogenic Escherichia coli strain reveals the acquisition of genetic elements associated with extra-intestinal pathogenicity.BMC genomics · 2014Article
- Article
- Article
- Point mutations in FimH adhesin of Crohn's disease-associated adherent-invasive Escherichia coli enhance intestinal inflammatory response.PLoS pathogens · 2013Article
- Microevolution in fimH gene of mucosa-associated Escherichia coli strains isolated from pediatric patients with inflammatory bowel disease.Infection and immunity · 2012Article
- High-resolution two-locus clonal typing of extraintestinal pathogenic Escherichia coli.Applied and environmental microbiology · 2012Article
- Escherichia coli physiology and metabolism dictates adaptation to diverse host microenvironments.Current opinion in microbiology · 2012Review
- Epidemiologic Investigation of Extra-intestinal pathogenic E. coli (ExPEC) based on PCR phylogenetic group and fimH single nucleotide polymorphisms (SNPs) in China.International journal of molecular epidemiology and genetics · 2011Article
- Complete genome sequence of Crohn's disease-associated adherent-invasive E. coli strain LF82.PloS one · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Correlations between FimH mutations and virulence were established by studying a collection of human commensal and extraintestinal pathogenic Escherichia coli natural isolates. Pathoadaptive (A27V and, to a lesser extent, A119V) and "commensal-adaptive" (A202V) mutations were evidenced in B2 phylogenetic group strains. fimH phylogenetic analysis indicates that these pathoadaptive mutations occurred several times.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.