Evidence map›Paper›PMID 12760877›Full record

ArticleAntimicrobial agents and chemotherapy2003

Chlamydia pneumoniae resists antibiotics in lymphocytes.

Hiroyuki Yamaguchi, Herman Friedman, Mayumi Yamamoto, Keigo Yasuda, Yoshimasa Yamamoto

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. European journal of microbiology & immunology · 2019
    Article
  3. Review
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Hiroyuki YamaguchiDepartment of Medical Microbiology and Immunology, College of Medicine, University of South Florida, Tampa, Florida 33612, USA.
Herman Friedman
Mayumi Yamamoto
Keigo Yasuda
Yoshimasa Yamamoto
University of South Florida · USGifu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chlamydia pneumoniae infection of lymphocytes in blood has been well documented, and it is apparent that control of this pathogen in these cells may be critical in the development of chronic inflammatory diseases associated with infection by this bacterium. The activity of antibiotics against C. pneumoniae in lymphocytes was assessed in this study by utilizing an in vitro infection model with lymphoid cells. The results obtained indicated that although all of the antibiotics tested showed remarkable activity against bacterial growth in epithelial cells, C. pneumoniae in lymphocytes was less susceptible to antibiotics than was bacterial growth in epithelial cells, which are widely used for the evaluation of anti-C. pneumoniae antibiotics.

Indexed as

FluoroquinolonesAnimalsAnti-Bacterial AgentsAnti-Infective AgentsAzithromycinCells, CulturedChlamydia InfectionsChlamydophila pneumoniaeClarithromycinFemaleHumansLymphocytesMiceMice, Inbred BALB CMicrobial Sensitivity TestsMinocyclineAnti-Bacterial AgentsAnti-Infective AgentsAzithromycinClarithromycinFluoroquinolonesMinocyclineNaphthyridinesRNA, Bacterialtosufloxacin

Identifiers

PMID12760877
PMCPMC155834
OpenAlexW2166893842

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.