ArticleCurrent infectious disease reports2003
Immune Restoration Inflammatory Syndromes: The Dark Side of Successful Antiretroviral Treatment.
Article in Current infectious disease reports, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The role of viruses in human acute appendicitis: a systematic literature review.International journal of colorectal disease · 2023Pooled it
- Diffuse retinal dysfunction following immune reconstitution uveitis in patients with prior cytomegalovirus retinitis: a novel observation.Documenta ophthalmologica. Advances in ophthalmology · 2023Article
- Gastric Extramural Tumor Caused by Mycobacteria Infection With Immunoreconstitution Inflammatory Syndrome.Cureus · 2022Article
- The current understanding of overlap between characteristics of HIV-associated neurocognitive disorders and Alzheimer's disease.Journal of neurovirology · 2019Review
- Increase in HSV shedding at initiation of antiretroviral therapy and decrease in shedding over time on antiretroviral therapy in HIV and HSV-2 infected persons.AIDS (London, England) · 2018Observational
- Extracorporeal Membrane Oxygenation in a 29-Year-Old Man withTexas Heart Institute journal · 2018Article
- Immune reconstitution inflammatory syndrome: A therapeutic paradox.Indian dermatology online journal · 2012Article
- [Immune reconstitution syndrome].Zeitschrift fur Rheumatologie · 2012Article
- Primary cerebral lymphomatoid granulomatosis as an immune reconstitution inflammatory syndrome in AIDS.Journal of neurology · 2010Article
- The comorbidity of HIV-associated neurocognitive disorders and Alzheimer's disease: a foreseeable medical challenge in post-HAART era.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2009Review
- Clinical and microbiological features of HIV-associated tuberculous meningitis in Vietnamese adults.PloS one · 2008Article
- HIV-1 TAT inhibits microglial phagocytosis of Abeta peptide.International journal of clinical and experimental pathology · 2008Article
- Immune restoration inflammatory syndromes: apparently paradoxical clinical events after the initiation of HAART.Current HIV/AIDS reports · 2004Review
- [Immune restoration inflammatory syndromes].Der Internist · 2004Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prevalence of cellular immunodeficiency has increased due to rising use of immunosuppressive therapies and the pandemic spread of HIV infection. More recently, the introduction of highly active antiretroviral therapy (HAART) in HIV has led to significant immune reconstitution, even in patients with previously long-lasting secondary immunodeficiency. HAART reduces morbidity and mortality in HIV infection and also changes the clinical course of prevalent subclinical opportunistic infections or autoimmune diseases. Atypical inflammatory disorders develop after initiation of HAART and have been summarized as "immune reconstitution syndrome," "immune restoration disease," and "immune restoration inflammatory syndrome." However, diagnostic criteria and standards of therapy are yet to be defined. The awareness for these diseases is of increasing importance from a clinical point of view. This review summarizes the variety of immunoreconstitution disorders and describes possible diagnostic pitfalls. We also propose possible therapeutic options.
Identifiers
12760825What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.