Evidence map›Paper›PMID 12758278›Full record

ReviewMicrobes and infection2003

Vgamma2Vdelta2+ T cells and anti-microbial immune responses.

Zheng W Chen, Norman L Letvin

Open access · greenAbstract readReview
In one paragraph

Review in Microbes and infection, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 69 citations in OpenAlex.

  1. Enrichment of CD4iScience · 2026
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  3. Enrichment of a CD4bioRxiv : the preprint server for biology · 2025
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  4. Review
  5. Review
  6. NK-like CD8Science immunology · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zheng W ChenTuberculosis Research Unit, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, RE 113/213C, Boston MA 02115, USA. zchen@caregroup.harvard.edu
Norman L Letvin
Harvard University · US

Funding

MODEL OF AIDS VIRUS-RELATED PULMONARY TUBERCULOSISR01HL064560 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHEN, ZHENG W · 1999 to 2014
$9.5M
SIV/MYCOBACTERIUM COINFECTIONR01RR013601 · NCRR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHEN, ZHENG W · 1998 to 2008
$4.4M
NCRR NIH HHS R01 RR013601NCRR NIH HHS RR13601NHLBI NIH HHS HL64560NHLBI NIH HHS R01 HL064560
6 · The paper itself

Abstract

Vgamma2Vdelta2(+) T cells exist only in primates and constitute the majority of circulating human gammadelta T cells. Recent studies have demonstrated that this unique gammadelta T cell subpopulation can be a component of adaptive immune responses and contribute to anti-microbial immunity to infections.

Indexed as

AnimalsBacterial InfectionsHIV InfectionsHumansReceptors, Antigen, T-Cell, gamma-deltaT-LymphocytesTuberculosisReceptors, Antigen, T-Cell, gamma-delta

Identifiers

PMID12758278
PMCPMC2873077
OpenAlexW2055181136

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.