ArticleJournal of bacteriology2003
Error-prone polymerase, DNA polymerase IV, is responsible for transient hypermutation during adaptive mutation in Escherichia coli.
Article in Journal of bacteriology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 85 citations in OpenAlex.
- Gut microbe Lactiplantibacillus plantarum undergoes different evolutionary trajectories between insects and mammals.BMC biology · 2022Article
- Metabolic and evolutionary patterns in the extremely acidophilic archaeon Ferroplasma acidiphilum YScientific reports · 2017Article
- Mapping DNA polymerase errors by single-molecule sequencing.Nucleic acids research · 2016Article
- Interactions and Localization of Escherichia coli Error-Prone DNA Polymerase IV after DNA Damage.Journal of bacteriology · 2015Article
- Characterization of three mycobacterial DinB (DNA polymerase IV) paralogs highlights DinB2 as naturally adept at ribonucleotide incorporation.Nucleic acids research · 2014Article
- Translesion DNA polymerases.Cold Spring Harbor perspectives in biology · 2013Review
- A strategically located serine residue is critical for the mutator activity of DNA polymerase IV from Escherichia coli.Nucleic acids research · 2013Article
- Stress-Induced Mutagenesis.EcoSal Plus · 2012Article
- Translesion DNA Synthesis.EcoSal Plus · 2012Article
- Article
- Double-Strand Break Repair and Holliday Junction Processing Are Required for Chromosome Processing in Stationary-Phase Escherichia coli Cells.G3 (Bethesda, Md.) · 2011Article
- Escherichia coli Rep DNA helicase and error-prone DNA polymerase IV interact physically and functionally.Molecular microbiology · 2011Article
- Mismatch repair modulation of MutY activity drives Bacillus subtilis stationary-phase mutagenesis.Journal of bacteriology · 2011Article
- Architecture of y-family DNA polymerases relevant to translesion DNA synthesis as revealed in structural and molecular modeling studies.Journal of nucleic acids · 2010Article
- Steric gate variants of UmuC confer UV hypersensitivity on Escherichia coli.Journal of bacteriology · 2009Article
- Bacteria as computers making computers.FEMS microbiology reviews · 2009Review
- DNA polymerase switching: effects on spontaneous mutagenesis in Escherichia coli.Molecular microbiology · 2009Article
- The optimal burst of mutation to create a phenotype.Journal of theoretical biology · 2008Article
- Role of polyphosphates in microbial adaptation to extreme environments.Applied and environmental microbiology · 2008Review
- UmuD and RecA directly modulate the mutagenic potential of the Y family DNA polymerase DinB.Molecular cell · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
The frequencies of nonselected mutations among adaptive Lac(+) revertants of Escherichia coli strains with and without the error-prone DNA polymerase IV (Pol IV) were compared. This frequency was more than sevenfold lower in the Pol IV-defective strain than in the wild-type strain. Thus, the mutations that occur during hypermutation are due to Pol IV.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.