ArticleGenetics2003
Continuous exchange of sequence information between dispersed Tc1 transposons in the Caenorhabditis elegans genome.
Article in Genetics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 57 citations in OpenAlex.
- Tissue-specific DNA repair strategies underlie apparent high transposon activity in the Caenorhabditis elegans soma.G3 (Bethesda, Md.) · 2026Article
- Transposable elements hitchhike on Starships across fungal genomes.Nature communications · 2026Article
- Transposon Regulation in thebioRxiv : the preprint server for biology · 2025Article
- Transposable elements and heterochromatic regions are enriched for structural variation and sequence divergence in the genome of wild-type Caenorhabditis elegans.G3 (Bethesda, Md.) · 2025Article
- Bioinformatic Annotation of Transposon DNA Processing Genes on the Long-Read Genome Assembly ofBioinformatics and biology insights · 2024Article
- Comprehensive detection of structural variation and transposable element differences between wild type laboratory lineages ofbioRxiv : the preprint server for biology · 2023Article
- Bergerac strains of Caenorhabditis elegans revisited: expansion of Tc1 elements imposes a significant genomic and fitness cost.G3 (Bethesda, Md.) · 2022Article
- Elevated Temperatures Cause Transposon-Associated DNA Damage in C. elegans Spermatocytes.Current biology : CB · 2020Article
- Article
- Becoming a Selfish Clan: Recombination Associated to Reverse-Transcription in LTR Retrotransposons.Genome biology and evolution · 2019Review
- Visualization and Quantification of Transposon Activity inG3 (Bethesda, Md.) · 2019Article
- Mobilization of Pack-CACTA transposons in Arabidopsis suggests the mechanism of gene shuffling.Nucleic acids research · 2019Article
- Natural Variation in the Distribution and Abundance of Transposable Elements Across the Caenorhabditis elegans Species.Molecular biology and evolution · 2017Article
- DNA transposon-based gene vehicles - scenes from an evolutionary drive.Journal of biomedical science · 2013Review
- Evolution of a transposon in Daphnia hybrid genomes.Mobile DNA · 2013Article
- MUT-16 promotes formation of perinuclear mutator foci required for RNA silencing in the C. elegans germline.Genes & development · 2012Article
- The ERI-6/7 helicase acts at the first stage of an siRNA amplification pathway that targets recent gene duplications.PLoS genetics · 2011Article
- The bacterial Tn9 chloramphenicol resistance gene: an attractive DNA segment for Mos1 mariner insertions.Molecular genetics and genomics : MGG · 2009Article
- Gene conversion and end-joining-repair double-strand breaks in the Caenorhabditis elegans germline.Genetics · 2008Article
- Transposon excision from an atypical site: a mechanism of evolution of novel transposable elements.PloS one · 2007Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In a genome-wide analysis of the active transposons in Caenorhabditis elegans we determined the localization and sequence of all copies of each of the six active transposon families. Most copies of the most active transposons, Tc1 and Tc3, are intact but individually have a unique sequence, because of unique patterns of single-nucleotide polymorphisms. The sequence of each of the 32 Tc1 elements is invariant in the C. elegans strain N2, which has no germline transposition. However, at the same 32 Tc1 loci in strains with germline transposition, Tc1 elements can acquire the sequence of Tc1 elements elsewhere in the N2 genome or a chimeric sequence derived from two dispersed Tc1 elements. We hypothesize that during double-strand-break repair after Tc1 excision, the template for repair can switch from the Tc1 element on the sister chromatid or homologous chromosome to a Tc1 copy elsewhere in the genome. Thus, the population of active transposable elements in C. elegans is highly dynamic because of a continuous exchange of sequence information between individual copies, potentially allowing a higher evolution rate than that found in endogenous genes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.